抄録
We examined the autopsied brains of two parkinsonian patients who had malignant syndrome (MS). Neopterin and biopterin contents, and GTP cyclohydrolase I activity were measured in various region of the brain. We found relatively higher GTP cyclohydrolase I activities in the hypothalamus compared with other regions of the brain from patients with MS. This finding suggested a possible involvement of biopterin metabolism in pathophysiology of MS. This is the first report on biopterin metabolism in the brains of patients with MS.
本文言語 | English |
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ページ(範囲) | 11-14 |
ページ数 | 4 |
ジャーナル | Parkinsonism and Related Disorders |
巻 | 9 |
号 | SUPPL. 1 |
DOI | |
出版ステータス | Published - 04-2003 |
All Science Journal Classification (ASJC) codes
- 神経学
- 老年医学
- 臨床神経学