Budding and direct division of adult human erythrocytes in serum-free cultures

Gen Niimi, Koji Ohashi, I. D.E. Tomihiko, Jaime Pereda

研究成果: Article査読

抄録

This paper documents the budding and division process of human erythrocytes in vitro using time-lapse light microscopy of hanging-drop preparations. The erythrocytes were prepared from normal adult human peripheral blood. Red blood cells showed cytoplasmic budding, segmentation, and direct division with delayed addition of erythropoietin in serum-free Dulbecco's modified Eagle's medium/nutrient mixture F-12 Ham. These observations are thought to be useful for developing model of definitive erythropoiesis and simple expansion of human erythrocytes.

本文言語English
ページ(範囲)73-77
ページ数5
ジャーナルOkajimas Folia Anatomica Japonica
86
3
DOI
出版ステータスPublished - 11-2009

All Science Journal Classification (ASJC) codes

  • 解剖学

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