C1Q complexes with beta-2-microglobulin and amyloid P-component in sera of patients with dialysis-associated amyloidosis

M. Hasegawa, S. Kawashima, M. Shikano, K. Kojima, T. Yanai, H. Hassegawa, M. Tomita, K. Murakami, N. Kawamura, H. Katsumata

研究成果: Article査読

4 被引用数 (Scopus)

抄録

We studied complexes composed of C1q and β2-microglobulin (C1q·β2M) or serum amyloid P-component (C1q·SAP) in the sera of 38 patients receiving hemodialysis (HD) and 20 healthy control subjects using an enzyme-linked immunoassay. We also compared complex levels in HD patients with and without symptoms of HD-associated amyloidosis (HA). Serum C1q·β2M levels were significantly higher in HD patients without HA than in healthy control subjects and significantly higher in HD patients with HA than in MD patients without HA. Serum C1q·SAP levels were significantly lower in patients with HA than in those without HA. These results suggest that C1q·β2M may contribute to HA.

本文言語English
ページ(範囲)380-383
ページ数4
ジャーナルNephron
69
4
DOI
出版ステータスPublished - 1995

All Science Journal Classification (ASJC) codes

  • 生理学
  • 腎臓病学
  • 生理学(医学)
  • 泌尿器学

フィンガープリント

「C1Q complexes with beta-2-microglobulin and amyloid P-component in sera of patients with dialysis-associated amyloidosis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル