Can we expand the indications for laparoscopic liver resection? A systematic review and meta-analysis of laparoscopic liver resection for patients with hepatocellular carcinoma and chronic liver disease

Zenichi Morise, Ruben Ciria, Daniel Cherqui, Kuo Hsin Chen, Giulio Belli, Go Wakabayashi

研究成果: ジャーナルへの寄稿学術論文査読

137 被引用数 (Scopus)

抄録

Abstract Liver resection (LR) for patients with hepatocellular carcinoma (HCC) and chronic liver disease (CLD) poses a high risk of serious postoperative complications and multicentric metachronous lesions requiring repeated treatment. The efficacy of laparoscopic LR (LLR) for such patients has yet to be established. The objective of this study is to test the outcomes of LLR for HCC with the aim of considering potential expansion of the indications for LLR. We performed a systematic review of the pertinent English-language literature. Our search yielded four meta-analyses and 23 comparative studies of LLR for HCC. On the basis of the findings from these studies and our newly conducted meta-analysis, the possibility for expanding the indications for LLR to HCC was examined. The studies show that LLR (vs open) for HCC generally yields better short-term outcomes without compromising long-term outcomes, and that incidences of postoperative ascites and liver failure are decreased with LLR. Several studies show the benefits of LLR for patients with severe CLD and for repeat surgery. Reductions of postoperative ascites and liver failure are among the advantages of LLR. These characteristics of LLR may allow us to expand the indications of LLR to HCC with CLD.

本文言語英語
ページ(範囲)342-352
ページ数11
ジャーナルJournal of Hepato-Biliary-Pancreatic Sciences
22
5
DOI
出版ステータス出版済み - 01-05-2015

All Science Journal Classification (ASJC) codes

  • 外科
  • 肝臓学

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