Case of complete response to neoadjuvant therapy using nivolumab in a patient with metastatic renal cell carcinoma

Daiki Ikarashi; Yoichiro Kato; Hirokatsu Katagiri; Takeshi Takahara; Noriyuki Uesugi; Ei Shiomi; Jun Sugimura; Hiroyuki Nitta; Tamotsu Sugai; Wataru Obara

doi:10.1111/iju.13590

Case of complete response to neoadjuvant therapy using nivolumab in a patient with metastatic renal cell carcinoma

Daiki Ikarashi, Yoichiro Kato, Hirokatsu Katagiri, Takeshi Takahara, Noriyuki Uesugi, Ei Shiomi, Jun Sugimura, Hiroyuki Nitta, Tamotsu Sugai, Wataru Obara

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

28 被引用数 (Scopus)

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Here, we report a case of a 68-year-old woman with cT4N0M1 (liver invasion and multiple lung metastases) metastatic renal cell carcinoma. We could carry out less invasive nephrectomy with partial hepatectomy because nivolumab administration as second-line therapy reduced the primary tumor remarkably. To the best of our knowledge, this is the first report of the use of nivolumab before carrying out surgery, and histological findings showed a pathological complete response.

本文言語	英語
ページ（範囲）	630-632
ページ数	3
ジャーナル	International Journal of Urology
巻	25
号	6
DOI	https://doi.org/10.1111/iju.13590
出版ステータス	出版済み - 06-2018
外部発表	はい

All Science Journal Classification (ASJC) codes

泌尿器学

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10.1111/iju.13590

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AU - Ikarashi, Daiki

AU - Kato, Yoichiro

AU - Katagiri, Hirokatsu

AU - Takahara, Takeshi

AU - Uesugi, Noriyuki

AU - Shiomi, Ei

AU - Sugimura, Jun

AU - Nitta, Hiroyuki

AU - Sugai, Tamotsu

AU - Obara, Wataru

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AB - Here, we report a case of a 68-year-old woman with cT4N0M1 (liver invasion and multiple lung metastases) metastatic renal cell carcinoma. We could carry out less invasive nephrectomy with partial hepatectomy because nivolumab administration as second-line therapy reduced the primary tumor remarkably. To the best of our knowledge, this is the first report of the use of nivolumab before carrying out surgery, and histological findings showed a pathological complete response.

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Case of complete response to neoadjuvant therapy using nivolumab in a patient with metastatic renal cell carcinoma

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