CD68+ Reactive histiocytosis complicating early gastric cancer

Yukari Ogawa, Ken‐ichi ‐i Inada, Yutaka Tsutsumi

研究成果: Article

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A peculiar form of reactive, non‐granulomatous proliferation of CD68+ histiocytes was demonstrated, for the first time, in the submucosal layer just beneath the IIa‐type early gastric adenocarcinoma that focally invaded submucosal lymphatics. The histiocytic cells possessed plump eosino‐philic and often foamy cytoplasm and eccentric small nuclei with apparent nucleoli. They contained periodic acid‐Schiff‐reactive granules, and were further immunoreactive for lysoryme and α1‐antttrypsin. The infiltration was ill‐defined, and partly involved the tunica muscularis mucosae and the proper muscle layer. Markers of epithelial cells, Langerhans' histiocytes, smooth muscle cells and myofibroblasts were all negative.

元の言語English
ページ(範囲)698-701
ページ数4
ジャーナルPathology International
45
発行部数9
DOI
出版物ステータスPublished - 09-1995
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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