抄録
This 32-year-old woman, 27 weeks pregnant, harbored a cystic mass with a solid component in the left frontal lobe. Histologically, the lesion was hypercellular and contained a diffuse sheet of eosinophilic cells of various sizes. The cells were almost round and had a few prominent, eccentrically placed, hyperchromatic nuclei of various sizes. Immunohistochemically, the tumor was reactive for vimentin, epithelial membrane antigen, cytokeratin AE1/ AE3, smooth muscle actin, and BAF47/INI-1, and negative for glial fibrillary acidic protein, neurofilament protein, S100 protein, CK7, CK20, HMB-45, MIC2, and Bcl-2. The Ki 67 labeling index was 4.2%. Comparative genomic hybridization analysis revealed aberrations of the chromosomal copy number of +7 and -10. This tumor could not be categorized according to the present World Health Organization classification. Results of staining with glial fibrillary acidic protein were not consistent with a glioma, and staining with INI-1 was inconsistent with atypical teratoid/rhabdoid tumor. The tumor was therefore designated as a "cerebral tumor with extensive rhabdoid features.".
| 元の言語 | English |
|---|---|
| ページ（範囲） | 492-496 |
| ページ数 | 5 |
| ジャーナル | Journal of Neurosurgery |
| 巻 | 111 |
| 発行部数 | 3 |
| DOI | |
| 出版物ステータス | Published - 07-12-2009 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Medicine(all)
- Clinical Neurology
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Cerebral tumor with extensive rhabdoid features and a favorable prognosis : Case report. / Oba, Shigeo; Yoshida, Kazunari; Hirose, Yuichi; Ikeda, Eiji; Nakazato, Yoichi; Kawase, Takeshi.
：: Journal of Neurosurgery, 巻 111, 番号 3, 07.12.2009, p. 492-496.研究成果: Article
TY - JOUR
T1 - Cerebral tumor with extensive rhabdoid features and a favorable prognosis
T2 - Case report
AU - Oba, Shigeo
AU - Yoshida, Kazunari
AU - Hirose, Yuichi
AU - Ikeda, Eiji
AU - Nakazato, Yoichi
AU - Kawase, Takeshi
PY - 2009/12/7
Y1 - 2009/12/7
N2 - This 32-year-old woman, 27 weeks pregnant, harbored a cystic mass with a solid component in the left frontal lobe. Histologically, the lesion was hypercellular and contained a diffuse sheet of eosinophilic cells of various sizes. The cells were almost round and had a few prominent, eccentrically placed, hyperchromatic nuclei of various sizes. Immunohistochemically, the tumor was reactive for vimentin, epithelial membrane antigen, cytokeratin AE1/ AE3, smooth muscle actin, and BAF47/INI-1, and negative for glial fibrillary acidic protein, neurofilament protein, S100 protein, CK7, CK20, HMB-45, MIC2, and Bcl-2. The Ki 67 labeling index was 4.2%. Comparative genomic hybridization analysis revealed aberrations of the chromosomal copy number of +7 and -10. This tumor could not be categorized according to the present World Health Organization classification. Results of staining with glial fibrillary acidic protein were not consistent with a glioma, and staining with INI-1 was inconsistent with atypical teratoid/rhabdoid tumor. The tumor was therefore designated as a "cerebral tumor with extensive rhabdoid features.".
AB - This 32-year-old woman, 27 weeks pregnant, harbored a cystic mass with a solid component in the left frontal lobe. Histologically, the lesion was hypercellular and contained a diffuse sheet of eosinophilic cells of various sizes. The cells were almost round and had a few prominent, eccentrically placed, hyperchromatic nuclei of various sizes. Immunohistochemically, the tumor was reactive for vimentin, epithelial membrane antigen, cytokeratin AE1/ AE3, smooth muscle actin, and BAF47/INI-1, and negative for glial fibrillary acidic protein, neurofilament protein, S100 protein, CK7, CK20, HMB-45, MIC2, and Bcl-2. The Ki 67 labeling index was 4.2%. Comparative genomic hybridization analysis revealed aberrations of the chromosomal copy number of +7 and -10. This tumor could not be categorized according to the present World Health Organization classification. Results of staining with glial fibrillary acidic protein were not consistent with a glioma, and staining with INI-1 was inconsistent with atypical teratoid/rhabdoid tumor. The tumor was therefore designated as a "cerebral tumor with extensive rhabdoid features.".
UR - http://www.scopus.com/inward/record.url?scp=70350495994&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70350495994&partnerID=8YFLogxK
U2 - 10.3171/2008.11.JNS08776
DO - 10.3171/2008.11.JNS08776
M3 - Article
C2 - 19231929
AN - SCOPUS:70350495994
VL - 111
SP - 492
EP - 496
JO - Journal of Neurosurgery
JF - Journal of Neurosurgery
SN - 0022-3085
IS - 3
ER -