Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

Mikio Hirayama, Tadanori Hamano, Masayuki Shiratori, Tatsuro Mutoh, Takanori Kumano, Takashi Aita, Masaru Kuriyama

研究成果: Article査読

9 被引用数 (Scopus)

抄録

A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.

本文言語English
ページ(範囲)23-24
ページ数2
ジャーナルJournal of the Neurological Sciences
151
1
DOI
出版ステータスPublished - 03-10-1997
外部発表はい

All Science Journal Classification (ASJC) codes

  • 神経学
  • 臨床神経学

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