Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

Mikio Hirayama; Tadanori Hamano; Masayuki Shiratori; Tatsuro Mutoh; Takanori Kumano; Takashi Aita; Masaru Kuriyama

doi:10.1016/S0022-510X(97)00072-5

Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

Mikio Hirayama
, Tadanori Hamano
, Masayuki Shiratori
, Tatsuro Mutoh
, Takanori Kumano
, Takashi Aita
, Masaru Kuriyama

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

抄録

A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.

本文言語	英語
ページ（範囲）	23-24
ページ数	2
ジャーナル	Journal of the Neurological Sciences
巻	151
号	1
DOI	https://doi.org/10.1016/S0022-510X(97)00072-5
出版ステータス	出版済み - 03-10-1997
外部発表	はい

All Science Journal Classification (ASJC) codes

神経学
臨床神経学

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10.1016/S0022-510X(97)00072-5

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abstract = "A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.",

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AU - Hirayama, Mikio

AU - Hamano, Tadanori

AU - Shiratori, Masayuki

AU - Mutoh, Tatsuro

AU - Kumano, Takanori

AU - Aita, Takashi

AU - Kuriyama, Masaru

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Y1 - 1997/10/3

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AB - A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement- mediated liposome immune lysis assay (LILA). This is the first demonstration of such antibodies in chorea-acanthocytosis. Anti-GM1 antibodies might have directly caused the axonal neuropathy by binding to GM1 or cross-reactive antigens in the nerves.

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Chorea-acanthocytosis with polyclonal antibodies to ganglioside GM1

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