Chronic social defeat stress induces the down-regulation of the Nedd4L-GLT-1 ubiquitination pathway in the prefrontal cortex of mice

Keyphrases

• Prefrontal Cortex 100%
• Glutamate Transporter 1 (GLT-1) 100%
• NEDD4 100%
• Chronic Social Defeat Stress 100%
• Ubiquitination Pathway 100%
• Ubiquitination 50%
• Major Depressive Disorder 37%
• Social Impairment 37%
• Pathophysiology 25%
• Consecutive Days 12%
• Social Interaction Test 12%
• C57BL 12%
• Molecular Mechanism 12%
• Male Mice 12%
• Glutamatergic Dysfunction 12%
• Depolarization 12%
• High Potassium 12%
• Downregulated Genes 12%
• Glutamate Release 12%
• UBE2T 12%
• Extracellular Glutamate 12%
• Brain Microdialysis 12%
• E3 Ligase 12%
• Stressful Life Events 12%
• Stress Exposure 12%
• Potassium Activation 12%
• Aggressor 12%
• Deubiquitinating Enzyme 12%
• Neural Precursor Cells 12%
• Ubiquitin System 12%
• Novel Antidepressant 12%

Neuroscience

• Prefrontal Cortex 100%
• Ubiquitination 100%
• Vesicular Glutamate Transporter 1 100%
• Social Defeat 100%
• Major Depressive Disorder 37%
• Glutamic Acid 25%
• Social Interaction 12%
• Antidepressant 12%
• Ligase 12%
• Ubiquitin Conjugating Enzyme E2 12%
• Ubiquitin Conjugating Enzyme 12%
• Microdialysis 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Vesicular Glutamate Transporter 1 100%
• Major Depression 37%
• Glutamic Acid 25%
• Pathophysiology 25%
• C57BL 6 Mouse 12%
• Hyperkalemia 12%
• Microdialysis 12%
• Antidepressant 12%
• Ligase 12%
• Ubiquitin Conjugating Enzyme 12%
• Ubiquitin Conjugating Enzyme E2 12%