Classic Hodgkin lymphoma with osseous involvement mimicking Langerhans cell histiocytosis in a child

Kazuhiko Kuwahara, Ko Kudo, Akiko Yashima-Abo, Kosuke Katayama, Keiko Kojima, Kiyoshi Tone, Etsuro Ito, Atsuko Nakazawa, Hideto Iwafuchi, Akira Kurose

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Hodgkin lymphoma (HL) commonly presents superficial lymphadenopathy. In addition, HL cells can arise in various organs including the liver and spleen as an extranodal lymphoma. HL in bone is unusual at the initial diagnosis, although some cases show late-stage localization of lymphoma cells to bone. We report the rare case of a young patient with cranial bone classic HL, presumably originating from the skull without any involvement of lymph nodes. As the main clinical manifestation was only tumor mass in the skull without osteoscopic pain, the tentative diagnosis of Langerhans cell histiocytosis was histologically confirmed by an excisional biopsy. Before the final pathological diagnosis as classic HL, we noticed several small lesions in extranodal regions through systemic surveys, suggesting that the cranial lesion appeared antecedent to those lesions. This is a rare and instructive case of cranial bone HL for which a histological diagnosis has been meticulously made.

本文言語English
ページ(範囲)147-151
ページ数5
ジャーナルHuman Pathology
77
DOI
出版ステータスPublished - 07-2018
外部発表はい

All Science Journal Classification (ASJC) codes

  • 病理学および法医学

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