Clinical efficacy and possible local hyperthermia mechanisms in allergic rhinitis II

Sho Miyata, Kensei Naito, Toshiko Mamiya

研究成果: Article査読

抄録

To determine possible nasal inhalation mechanisms in heated aerosol in treating allergic rhinitis, we measured nasal resistance before and after antigen or histamine challenge to nasal mucosa in nasal allergy patients treated and untreated by local hyperthermia. In antigen stimulation, mean nasal resistance in the group treated with local heated aerosol was significantly lower than that in the untreated group at early and late allergic reaction phases. In histamine stimulation, mean nasal resistance in the treated group was significantly lower and mean sneezing time was shorter than in the untreated group. We consider suppressed chemical mediator release from mast cells and decreased nonspecific hypersensitivity in allergic nasal mucosa to be possible mechanisms behind the effectiveness of heated local aerosol therapy.

本文言語English
ページ(範囲)70-75
ページ数6
ジャーナルOto-Rhino-Laryngology Tokyo
45
SUPPL. 1
出版ステータスPublished - 18-09-2002
外部発表はい

All Science Journal Classification (ASJC) codes

  • 耳鼻咽喉科学

フィンガープリント

「Clinical efficacy and possible local hyperthermia mechanisms in allergic rhinitis II」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル