Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome

Hideaki Matsuura, Akira Yamada, Kunihiko Sugimoto, Keiko Sugimoto, Masatsugu Iwase, Takashi Ishikawa, Junichi Ishii, Yukio Ozaki

研究成果: Article

抄録

Purpose The ratio of the left atrial volume index (LAVI) and late diastolic mitral annular velocity (A′) is a useful echocardiographic index for identifying advanced left ventricular (LV) diastolic dysfunction in patients with dyspnoea. We investigated the clinical implications and prognostic value of the aforementioned ratio (LAVI/A′) in patients with ST elevation (STE) or non-STE (NSTE) acute coronary syndrome (ACS). Methods We studied 212 patients with ACS. All patients underwent electrocardiography, echocardiography and measurement of plasma B-type natriuretic peptide (BNP) level on admission. The study endpoints were hospitalisation and mortality because of heart failure (HF). Results There was a significant, moderate positive correlation between LAVI/A′ and natural logarithm (Ln) BNP level among the participants (r=0.48, p<0.0001). During a mean follow-up of 17 months, eight patients died and nine patients were hospitalised because of HF. The receiver operating characteristics curve indicated that LAVI/A′≥3.0 predicted these events (log-rank, p=0.0021). A significant and moderate positive correlation existed between LAVI/A′ and Ln BNP level in the NSTE-ACS group (n=128; r=0.58, p<0.0001). However, the correlation between LAVI/A′ and Ln BNP level was weaker in the STE-ACS group (n=84; r=0.33, p=0.0017). Conclusion LAVI/A′ was related to plasma BNP levels in patients with ACS, particularly in those with NSTE-ACS. This index was useful for predicting cardiac events in patients with ACS.

元の言語English
記事番号e011038
ジャーナルHeart Asia
10
発行部数2
DOI
出版物ステータスPublished - 01-06-2018

Fingerprint

Acute Coronary Syndrome
Brain Natriuretic Peptide
Heart Failure
Left Ventricular Dysfunction
ROC Curve
Dyspnea
Echocardiography
Electrocardiography
Hospitalization
Mortality

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

これを引用

Matsuura, H., Yamada, A., Sugimoto, K., Sugimoto, K., Iwase, M., Ishikawa, T., ... Ozaki, Y. (2018). Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome. Heart Asia, 10(2), [e011038]. https://doi.org/10.1136/heartasia-2018-011038
Matsuura, Hideaki ; Yamada, Akira ; Sugimoto, Kunihiko ; Sugimoto, Keiko ; Iwase, Masatsugu ; Ishikawa, Takashi ; Ishii, Junichi ; Ozaki, Yukio. / Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome. :: Heart Asia. 2018 ; 巻 10, 番号 2.
@article{18d19b6cf4ce466c851de33d0982baa6,
title = "Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome",
abstract = "Purpose The ratio of the left atrial volume index (LAVI) and late diastolic mitral annular velocity (A′) is a useful echocardiographic index for identifying advanced left ventricular (LV) diastolic dysfunction in patients with dyspnoea. We investigated the clinical implications and prognostic value of the aforementioned ratio (LAVI/A′) in patients with ST elevation (STE) or non-STE (NSTE) acute coronary syndrome (ACS). Methods We studied 212 patients with ACS. All patients underwent electrocardiography, echocardiography and measurement of plasma B-type natriuretic peptide (BNP) level on admission. The study endpoints were hospitalisation and mortality because of heart failure (HF). Results There was a significant, moderate positive correlation between LAVI/A′ and natural logarithm (Ln) BNP level among the participants (r=0.48, p<0.0001). During a mean follow-up of 17 months, eight patients died and nine patients were hospitalised because of HF. The receiver operating characteristics curve indicated that LAVI/A′≥3.0 predicted these events (log-rank, p=0.0021). A significant and moderate positive correlation existed between LAVI/A′ and Ln BNP level in the NSTE-ACS group (n=128; r=0.58, p<0.0001). However, the correlation between LAVI/A′ and Ln BNP level was weaker in the STE-ACS group (n=84; r=0.33, p=0.0017). Conclusion LAVI/A′ was related to plasma BNP levels in patients with ACS, particularly in those with NSTE-ACS. This index was useful for predicting cardiac events in patients with ACS.",
author = "Hideaki Matsuura and Akira Yamada and Kunihiko Sugimoto and Keiko Sugimoto and Masatsugu Iwase and Takashi Ishikawa and Junichi Ishii and Yukio Ozaki",
year = "2018",
month = "6",
day = "1",
doi = "10.1136/heartasia-2018-011038",
language = "English",
volume = "10",
journal = "Heart Asia",
issn = "1759-1104",
publisher = "BMJ Publishing Group",
number = "2",

}

Matsuura, H, Yamada, A, Sugimoto, K, Sugimoto, K, Iwase, M, Ishikawa, T, Ishii, J & Ozaki, Y 2018, 'Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome', Heart Asia, 巻. 10, 番号 2, e011038. https://doi.org/10.1136/heartasia-2018-011038

Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome. / Matsuura, Hideaki; Yamada, Akira; Sugimoto, Kunihiko; Sugimoto, Keiko; Iwase, Masatsugu; Ishikawa, Takashi; Ishii, Junichi; Ozaki, Yukio.

:: Heart Asia, 巻 10, 番号 2, e011038, 01.06.2018.

研究成果: Article

TY - JOUR

T1 - Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome

AU - Matsuura, Hideaki

AU - Yamada, Akira

AU - Sugimoto, Kunihiko

AU - Sugimoto, Keiko

AU - Iwase, Masatsugu

AU - Ishikawa, Takashi

AU - Ishii, Junichi

AU - Ozaki, Yukio

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Purpose The ratio of the left atrial volume index (LAVI) and late diastolic mitral annular velocity (A′) is a useful echocardiographic index for identifying advanced left ventricular (LV) diastolic dysfunction in patients with dyspnoea. We investigated the clinical implications and prognostic value of the aforementioned ratio (LAVI/A′) in patients with ST elevation (STE) or non-STE (NSTE) acute coronary syndrome (ACS). Methods We studied 212 patients with ACS. All patients underwent electrocardiography, echocardiography and measurement of plasma B-type natriuretic peptide (BNP) level on admission. The study endpoints were hospitalisation and mortality because of heart failure (HF). Results There was a significant, moderate positive correlation between LAVI/A′ and natural logarithm (Ln) BNP level among the participants (r=0.48, p<0.0001). During a mean follow-up of 17 months, eight patients died and nine patients were hospitalised because of HF. The receiver operating characteristics curve indicated that LAVI/A′≥3.0 predicted these events (log-rank, p=0.0021). A significant and moderate positive correlation existed between LAVI/A′ and Ln BNP level in the NSTE-ACS group (n=128; r=0.58, p<0.0001). However, the correlation between LAVI/A′ and Ln BNP level was weaker in the STE-ACS group (n=84; r=0.33, p=0.0017). Conclusion LAVI/A′ was related to plasma BNP levels in patients with ACS, particularly in those with NSTE-ACS. This index was useful for predicting cardiac events in patients with ACS.

AB - Purpose The ratio of the left atrial volume index (LAVI) and late diastolic mitral annular velocity (A′) is a useful echocardiographic index for identifying advanced left ventricular (LV) diastolic dysfunction in patients with dyspnoea. We investigated the clinical implications and prognostic value of the aforementioned ratio (LAVI/A′) in patients with ST elevation (STE) or non-STE (NSTE) acute coronary syndrome (ACS). Methods We studied 212 patients with ACS. All patients underwent electrocardiography, echocardiography and measurement of plasma B-type natriuretic peptide (BNP) level on admission. The study endpoints were hospitalisation and mortality because of heart failure (HF). Results There was a significant, moderate positive correlation between LAVI/A′ and natural logarithm (Ln) BNP level among the participants (r=0.48, p<0.0001). During a mean follow-up of 17 months, eight patients died and nine patients were hospitalised because of HF. The receiver operating characteristics curve indicated that LAVI/A′≥3.0 predicted these events (log-rank, p=0.0021). A significant and moderate positive correlation existed between LAVI/A′ and Ln BNP level in the NSTE-ACS group (n=128; r=0.58, p<0.0001). However, the correlation between LAVI/A′ and Ln BNP level was weaker in the STE-ACS group (n=84; r=0.33, p=0.0017). Conclusion LAVI/A′ was related to plasma BNP levels in patients with ACS, particularly in those with NSTE-ACS. This index was useful for predicting cardiac events in patients with ACS.

UR - http://www.scopus.com/inward/record.url?scp=85049478237&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049478237&partnerID=8YFLogxK

U2 - 10.1136/heartasia-2018-011038

DO - 10.1136/heartasia-2018-011038

M3 - Article

AN - SCOPUS:85049478237

VL - 10

JO - Heart Asia

JF - Heart Asia

SN - 1759-1104

IS - 2

M1 - e011038

ER -

Matsuura H, Yamada A, Sugimoto K, Sugimoto K, Iwase M, Ishikawa T その他. Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome. Heart Asia. 2018 6 1;10(2). e011038. https://doi.org/10.1136/heartasia-2018-011038