Clinical significance of changes in electrocardiographic R-wave voltage on chest leads in patients with acute anterior myocardial infarction

Satoshi Isobe, Mitsuhiro Okada, Akitada Ando, Mamoru Nanasato, Makoto Nonokawa, Hideo Izawa, Takahisa Kondo, Makoto Hirai, Mitsuhiro Yokota, Yoshifumi Tanahashi, Hidehiko Saito

研究成果: Article査読

8 被引用数 (Scopus)

抄録

This article aims to clarify the clinical significance of changes in electrocardiographic (ECG) R-wave voltage on chest leads from 1 to 4 weeks in patients with acute anterior myocardial infarction (MI) in combination with echocardiographic findings and dual scintigraphic findings. Seventy-one patients with acute anterior MI who underwent emergency revascularization were subjected to ECG and echocardiography, at both 1 and 4 weeks, and to thallium-201 (TI) and iodine-123-β-methyl-p-iodophenyl pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) about 1 week after the onset of MI. The total sum of ECG R-wave voltage on each chest lead was calculated. The mean defect ratio on TI and that on BMIPP derived from circumferential profile curve analysis were calculated. The percentage defect-discordant ratio of both SPECT images [(%) discordance on TI/BMIPP] was obtained. The percentage increase ratio of ECG R-wave voltage on chest leads [(%) increase of R wave] and the increase of left ventricular ejection fraction (ΔEF) from 1 to 4 weeks were obtained. There were significant correlations between the (%) increase of R wave and the ΔEF as well as between the (%) increase of R wave and the (%) discordance on TI/BMIPP (r = .63, P < .001; r = .74, P < .001). The reversibility of ECG R-wave voltage was related to cardiac functional improvement in addition to the discordance on the 2 images. Monitoring of changes in ECG R-wave voltage on chest leads is useful to detect the presence of myocardial viability and to evaluate functional evolution in patients with acute anterior MI.

本文言語English
ページ(範囲)173-180
ページ数8
ジャーナルJournal of Electrocardiology
35
3
DOI
出版ステータスPublished - 2002
外部発表はい

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

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