Clinical study of NM441 on urinary tract infections

Keizo Suzuki; Masaki Horiba; Kiyohito Ishikawa; Yorio Naide; Kiyotaka Hoshinaga; Masanori Yanaoka; Shinobu Kato; Shinichi Ando; Norihiko Okishio; Haruyoshi Asano

Clinical study of NM441 on urinary tract infections

Keizo Suzuki, Masaki Horiba, Kiyohito Ishikawa, Yorio Naide, Kiyotaka Hoshinaga, Masanori Yanaoka, Shinobu Kato, Shinichi Ando, Norihiko Okishio, Haruyoshi Asano

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

抄録

NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.

本文言語	英語
ページ（範囲）	678-683
ページ数	6
ジャーナル	Japanese Journal of Chemotherapy
巻	44
号	SUPPL. 1
出版ステータス	出版済み - 1996
外部発表	はい

All Science Journal Classification (ASJC) codes

薬理学
薬理学（医学）

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引用スタイル

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title = "Clinical study of NM441 on urinary tract infections",

abstract = "NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.",

author = "Keizo Suzuki and Masaki Horiba and Kiyohito Ishikawa and Yorio Naide and Kiyotaka Hoshinaga and Masanori Yanaoka and Shinobu Kato and Shinichi Ando and Norihiko Okishio and Haruyoshi Asano",

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T1 - Clinical study of NM441 on urinary tract infections

AU - Suzuki, Keizo

AU - Horiba, Masaki

AU - Ishikawa, Kiyohito

AU - Naide, Yorio

AU - Hoshinaga, Kiyotaka

AU - Yanaoka, Masanori

AU - Kato, Shinobu

AU - Ando, Shinichi

AU - Okishio, Norihiko

AU - Asano, Haruyoshi

PY - 1996

Y1 - 1996

N2 - NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.

AB - NM441, a new oral quinolone antibiotic, was administered to 74 patients with urinary tract infections at a daily dose of 100~600mg for 3~47 days. The patients evaluable according to the criteria of the Japanese UTI Committee were 60 cases, and the clinical efficacy rates were 100% (11/11) in acute uncomplicated cystitis and 63.3% (31/49) in complicated urinary tract infections. Side effects were observed in a total of 5 cases; headache and nausea in 1 and digestive symptoms in 4. Abnormal laboratory findings were observed in a total of 3 cases; an elevation of GPT in 1, elevations of BUN and serum creatinine in 1 and an elevation of serum creatinine in 1.

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Clinical study of NM441 on urinary tract infections

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