[Clinicopathological features of peripheral small-sized (2 cm or less in diameter) non-small cell lung cancer].

Masaki Kawamura, Chiaki Endo, Takashi Kondo, Yoshinori Okada, Yasushi Hoshikawa, Akira Sakurada, Tetsu Sado, Masafumi Noda, Sumiko Maeda, Hisashi Oishi, Takaya Suzuki

研究成果: Article

抄録

Ninety-three patients with completely resected peripheral non-small cell lung cancer, clinically diagnosed 2 cm or less in diameter, were retrospectively reviewed. Their preoperative computed tomography (CT) and positron emission tomography (PET) findings, carcinoembryonic antigen (CEA) values, clinico-pathological features and postoperative outcomes were analysed. Ground-glass opacity (GGO) ratio( soft tissue density area of the tumor/maximum area of the tumor in diameter) was measured. The overall survival rate at 3 years was 93.3% and the relapse-free survival rate at 3 years was 89.4% with a median follow-up period of 38.5 months. Patients with GGO ratio 0.25 or less had no lymph node (LN) involvement nor lymph vascular invasion. Only 2 of them (8%) had vascular invasion. Fisher's exact probability test revealed CEA ≥ 5 ng/ ml as risk factor for LN involvement( p=0.0400). Multiple logistic regression analysis showed that solid adenocarcinoma and squamous cell carcinoma recurred more frequently than adenocarcinoma with GGO (p=0.0619, odds ratio 4.969, 95%CI 0.9242~37.67).

元の言語English
ページ(範囲)11-16
ページ数6
ジャーナルKyobu geka. The Japanese journal of thoracic surgery
65
発行部数1
出版物ステータスPublished - 01-01-2012

Fingerprint

Non-Small Cell Lung Carcinoma
Glass
Carcinoembryonic Antigen
Blood Vessels
Adenocarcinoma
Survival Rate
Lymph Nodes
Lymph
Squamous Cell Carcinoma
Neoplasms
Logistic Models
Odds Ratio
Regression Analysis
Recurrence
Positron Emission Tomography Computed Tomography

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Kawamura, Masaki ; Endo, Chiaki ; Kondo, Takashi ; Okada, Yoshinori ; Hoshikawa, Yasushi ; Sakurada, Akira ; Sado, Tetsu ; Noda, Masafumi ; Maeda, Sumiko ; Oishi, Hisashi ; Suzuki, Takaya. / [Clinicopathological features of peripheral small-sized (2 cm or less in diameter) non-small cell lung cancer]. :: Kyobu geka. The Japanese journal of thoracic surgery. 2012 ; 巻 65, 番号 1. pp. 11-16.
@article{542872eacaf14af0a60437306abb9062,
title = "[Clinicopathological features of peripheral small-sized (2 cm or less in diameter) non-small cell lung cancer].",
abstract = "Ninety-three patients with completely resected peripheral non-small cell lung cancer, clinically diagnosed 2 cm or less in diameter, were retrospectively reviewed. Their preoperative computed tomography (CT) and positron emission tomography (PET) findings, carcinoembryonic antigen (CEA) values, clinico-pathological features and postoperative outcomes were analysed. Ground-glass opacity (GGO) ratio( soft tissue density area of the tumor/maximum area of the tumor in diameter) was measured. The overall survival rate at 3 years was 93.3{\%} and the relapse-free survival rate at 3 years was 89.4{\%} with a median follow-up period of 38.5 months. Patients with GGO ratio 0.25 or less had no lymph node (LN) involvement nor lymph vascular invasion. Only 2 of them (8{\%}) had vascular invasion. Fisher's exact probability test revealed CEA ≥ 5 ng/ ml as risk factor for LN involvement( p=0.0400). Multiple logistic regression analysis showed that solid adenocarcinoma and squamous cell carcinoma recurred more frequently than adenocarcinoma with GGO (p=0.0619, odds ratio 4.969, 95{\%}CI 0.9242~37.67).",
author = "Masaki Kawamura and Chiaki Endo and Takashi Kondo and Yoshinori Okada and Yasushi Hoshikawa and Akira Sakurada and Tetsu Sado and Masafumi Noda and Sumiko Maeda and Hisashi Oishi and Takaya Suzuki",
year = "2012",
month = "1",
day = "1",
language = "English",
volume = "65",
pages = "11--16",
journal = "Japanese Journal of Thoracic Surgery",
issn = "0021-5252",
publisher = "Nankodo Co., Ltd.",
number = "1",

}

Kawamura, M, Endo, C, Kondo, T, Okada, Y, Hoshikawa, Y, Sakurada, A, Sado, T, Noda, M, Maeda, S, Oishi, H & Suzuki, T 2012, '[Clinicopathological features of peripheral small-sized (2 cm or less in diameter) non-small cell lung cancer].', Kyobu geka. The Japanese journal of thoracic surgery, 巻. 65, 番号 1, pp. 11-16.

[Clinicopathological features of peripheral small-sized (2 cm or less in diameter) non-small cell lung cancer]. / Kawamura, Masaki; Endo, Chiaki; Kondo, Takashi; Okada, Yoshinori; Hoshikawa, Yasushi; Sakurada, Akira; Sado, Tetsu; Noda, Masafumi; Maeda, Sumiko; Oishi, Hisashi; Suzuki, Takaya.

:: Kyobu geka. The Japanese journal of thoracic surgery, 巻 65, 番号 1, 01.01.2012, p. 11-16.

研究成果: Article

TY - JOUR

T1 - [Clinicopathological features of peripheral small-sized (2 cm or less in diameter) non-small cell lung cancer].

AU - Kawamura, Masaki

AU - Endo, Chiaki

AU - Kondo, Takashi

AU - Okada, Yoshinori

AU - Hoshikawa, Yasushi

AU - Sakurada, Akira

AU - Sado, Tetsu

AU - Noda, Masafumi

AU - Maeda, Sumiko

AU - Oishi, Hisashi

AU - Suzuki, Takaya

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Ninety-three patients with completely resected peripheral non-small cell lung cancer, clinically diagnosed 2 cm or less in diameter, were retrospectively reviewed. Their preoperative computed tomography (CT) and positron emission tomography (PET) findings, carcinoembryonic antigen (CEA) values, clinico-pathological features and postoperative outcomes were analysed. Ground-glass opacity (GGO) ratio( soft tissue density area of the tumor/maximum area of the tumor in diameter) was measured. The overall survival rate at 3 years was 93.3% and the relapse-free survival rate at 3 years was 89.4% with a median follow-up period of 38.5 months. Patients with GGO ratio 0.25 or less had no lymph node (LN) involvement nor lymph vascular invasion. Only 2 of them (8%) had vascular invasion. Fisher's exact probability test revealed CEA ≥ 5 ng/ ml as risk factor for LN involvement( p=0.0400). Multiple logistic regression analysis showed that solid adenocarcinoma and squamous cell carcinoma recurred more frequently than adenocarcinoma with GGO (p=0.0619, odds ratio 4.969, 95%CI 0.9242~37.67).

AB - Ninety-three patients with completely resected peripheral non-small cell lung cancer, clinically diagnosed 2 cm or less in diameter, were retrospectively reviewed. Their preoperative computed tomography (CT) and positron emission tomography (PET) findings, carcinoembryonic antigen (CEA) values, clinico-pathological features and postoperative outcomes were analysed. Ground-glass opacity (GGO) ratio( soft tissue density area of the tumor/maximum area of the tumor in diameter) was measured. The overall survival rate at 3 years was 93.3% and the relapse-free survival rate at 3 years was 89.4% with a median follow-up period of 38.5 months. Patients with GGO ratio 0.25 or less had no lymph node (LN) involvement nor lymph vascular invasion. Only 2 of them (8%) had vascular invasion. Fisher's exact probability test revealed CEA ≥ 5 ng/ ml as risk factor for LN involvement( p=0.0400). Multiple logistic regression analysis showed that solid adenocarcinoma and squamous cell carcinoma recurred more frequently than adenocarcinoma with GGO (p=0.0619, odds ratio 4.969, 95%CI 0.9242~37.67).

UR - http://www.scopus.com/inward/record.url?scp=84859394388&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84859394388&partnerID=8YFLogxK

M3 - Article

C2 - 22314150

AN - SCOPUS:84859394388

VL - 65

SP - 11

EP - 16

JO - Japanese Journal of Thoracic Surgery

JF - Japanese Journal of Thoracic Surgery

SN - 0021-5252

IS - 1

ER -