Cloning and sequencing of a novel human gene which encodes a putative hydroxylase

C. Iriyama, S. Matsuda, R. Katsumata, M. Hamaguchi

研究成果: Article査読

16 被引用数 (Scopus)

抄録

Using a conventional two-hybrid technique with MAWD as bait protein, a novel full-length cDNA was isolated and sequenced from a human liver cDNA library. This cDNA consists of 2575 base pairs and has a predicted open reading frame encoding 255 amino acids. Overall, it is similar to the catalytic enzyme PHZF, catalyzing the hydroxylation of phenazine-1-carboxylic acid to 2-hydroxy-phenazine-1-carboxylic acid. Polymerase chain reaction-based mapping with both a monochromosomal hybrid panel and radiation hybrid cell panels placed the gene to human chromosome 10q21.1 near the marker D10S210.

本文言語English
ページ(範囲)289-292
ページ数4
ジャーナルJournal of Human Genetics
46
5
DOI
出版ステータスPublished - 2001
外部発表はい

All Science Journal Classification (ASJC) codes

  • 遺伝学
  • 遺伝学(臨床)

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