Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

Takahide Nomura; Hiroshi Ichinose; Chiho Sumi-Ichinose; Hiroko Nomura; Yasumichi Hagino; Keisuke Fujita; Toshiharu Nagatsu

doi:10.1006/bbrc.1993.1249

Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

Takahide Nomura
, Hiroshi Ichinose
, Chiho Sumi-Ichinose
, Hiroko Nomura
, Yasumichi Hagino
, Keisuke Fujita
, Toshiharu Nagatsu

医学部・薬理学

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

50 被引用数 (Scopus)

抄録

A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96%) and human type 1(89%) enzymes.

本文言語	英語
ページ（範囲）	523-527
ページ数	5
ジャーナル	Biochemical and Biophysical Research Communications
巻	191
号	2
DOI	https://doi.org/10.1006/bbrc.1993.1249
出版ステータス	出版済み - 15-03-1993

All Science Journal Classification (ASJC) codes

生物理学
生化学
分子生物学
細胞生物学

文献へのアクセス

10.1006/bbrc.1993.1249

他のファイルとリンク

引用スタイル

@article{f73f2b7c1f754484b0bae1c6dce88284,

title = "Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1",

abstract = "A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96\%) and human type 1(89\%) enzymes.",

author = "Takahide Nomura and Hiroshi Ichinose and Chiho Sumi-Ichinose and Hiroko Nomura and Yasumichi Hagino and Keisuke Fujita and Toshiharu Nagatsu",

year = "1993",

month = mar,

day = "15",

doi = "10.1006/bbrc.1993.1249",

language = "English",

volume = "191",

pages = "523--527",

journal = "Biochemical and Biophysical Research Communications",

issn = "0006-291X",

publisher = "Elsevier B.V.",

number = "2",

}

TY - JOUR

T1 - Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

AU - Nomura, Takahide

AU - Ichinose, Hiroshi

AU - Sumi-Ichinose, Chiho

AU - Nomura, Hiroko

AU - Hagino, Yasumichi

AU - Fujita, Keisuke

AU - Nagatsu, Toshiharu

PY - 1993/3/15

Y1 - 1993/3/15

N2 - A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96%) and human type 1(89%) enzymes.

AB - A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96%) and human type 1(89%) enzymes.

UR - https://www.scopus.com/pages/publications/0027328913

UR - https://www.scopus.com/pages/publications/0027328913#tab=citedBy

U2 - 10.1006/bbrc.1993.1249

DO - 10.1006/bbrc.1993.1249

M3 - Article

C2 - 8461009

AN - SCOPUS:0027328913

SN - 0006-291X

VL - 191

SP - 523

EP - 527

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 2

ER -

Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

抄録

All Science Journal Classification (ASJC) codes

文献へのアクセス

他のファイルとリンク

フィンガープリント

引用スタイル