TY - JOUR
T1 - 表在型食道扁平上皮癌における linked color imaging で観察される色情報と深達度および血管径との相-に-する検討
AU - Kobayashi, Kenichi
AU - Miyahara, Ryoji
AU - Funasaka, Kohei
AU - Furukawa, Kazuhiro
AU - Sawada, Tsunaki
AU - Maeda, Keiko
AU - Yamamura, Takeshi
AU - Ishikawa, Takuya
AU - Ohno, Eizaburo
AU - Nakamura, Masanao
AU - Kawashima, Hiroki
AU - Nakaguro, Masato
AU - Okumura, Yuki
AU - Hirooka, Yoshiki
AU - Fujishiro, Mitsuhiro
N1 - Publisher Copyright:
© 2020 Japan Gastroenterological Endoscopy Society. All rights reserved.
PY - 2020/9
Y1 - 2020/9
N2 - Objectives: Accurate diagnosis of invasion depth is important for reliable treatment of esophageal squamous cell carcinoma (ESCC), but it is limited to the muscularis mucosae to slight submucosal invasion (MM/SM1). The diagnostic accuracy of invasion depth is unsatisfactory and remains to be improved. We aimed to investigate the association between the color of the superficial ESCC and invasion depth using linked color imaging (LCI) under light-emitting diode (LED) light sources. Methods: Lesions diagnosed as superficial ESCC were observed using white light imaging and then by LCI. The color values were calculated using Commission Internationale de l’Eclariage - L*a*b* color space, and the color difference was calculated according to invasion depth. The vascular diameters and vascular angles of the intrapapillary capillary loops were pathologically analyzed. Their correlation with mucosal color was also investigated by LCI. Results: In all, 52 lesions from 48 patients were analyzed. On the basis of invasion depth, the color difference between the normal mucosa and the lesion was larger in the MM/SM1 or deeper group than in the epithelium and the lamina propria mucosa (EP/LPM) group using LCI (P=0.025). The vascular diameter was positively correlated with the b* color value (correlation coefficient=0.302, P=0.033). Conclusion: Observation using LCI under LED light sources may improve the endoscopic diagnosis of the invasion depth of superficial ESCC. Further research is needed to validate its usefulness.
AB - Objectives: Accurate diagnosis of invasion depth is important for reliable treatment of esophageal squamous cell carcinoma (ESCC), but it is limited to the muscularis mucosae to slight submucosal invasion (MM/SM1). The diagnostic accuracy of invasion depth is unsatisfactory and remains to be improved. We aimed to investigate the association between the color of the superficial ESCC and invasion depth using linked color imaging (LCI) under light-emitting diode (LED) light sources. Methods: Lesions diagnosed as superficial ESCC were observed using white light imaging and then by LCI. The color values were calculated using Commission Internationale de l’Eclariage - L*a*b* color space, and the color difference was calculated according to invasion depth. The vascular diameters and vascular angles of the intrapapillary capillary loops were pathologically analyzed. Their correlation with mucosal color was also investigated by LCI. Results: In all, 52 lesions from 48 patients were analyzed. On the basis of invasion depth, the color difference between the normal mucosa and the lesion was larger in the MM/SM1 or deeper group than in the epithelium and the lamina propria mucosa (EP/LPM) group using LCI (P=0.025). The vascular diameter was positively correlated with the b* color value (correlation coefficient=0.302, P=0.033). Conclusion: Observation using LCI under LED light sources may improve the endoscopic diagnosis of the invasion depth of superficial ESCC. Further research is needed to validate its usefulness.
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U2 - 10.11280/gee.62.1624
DO - 10.11280/gee.62.1624
M3 - Article
AN - SCOPUS:85093980519
VL - 62
SP - 1624
EP - 1633
JO - Gastroenterological Endoscopy
JF - Gastroenterological Endoscopy
SN - 0387-1207
IS - 9
ER -