Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation

Report of a case

Shigeru Miyagawa, Goro Matsumiya, Toshihiro Funatsu, Masao Yoshitatsu, Naozumi Sekiya, Shinya Fukui, Takaya Hoashi, Masatsugu Hori, Hideki Yoshikawa, Yuzuru Kanakura, Jun Ishikawa, Katsuyuki Aozasa, Naomasa Kawaguchi, Nariaki Matsuura, Akira Myoui, Akifumi Matsuyama, Sachiko Ezoe, Hidehiro Iida, Hikaru Matsuda, Yoshiki Sawa

研究成果: Article

24 引用 (Scopus)

抄録

Myocardial regeneration therapy shows great promise as a treatment for heart failure. We recently introduced combined autologous cellular cardiomyoplasty with skeletal myoblasts and bone marrow cells as a treatment for human ischemic cardiomyopathy. We report the results of our first clinical trial of this technique, used to treat a patient with severe heart failure caused by ischemic cardiomyopathy who was being managed with a left ventricular assist system (LVAS). After combined cell transplantation, the patient showed signs of improved cardiac performance and angiogenesis, and reduced fibrosis.

元の言語English
ページ(範囲)133-136
ページ数4
ジャーナルSurgery Today
39
発行部数2
DOI
出版物ステータスPublished - 01-02-2009

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Cardiomyoplasty
Skeletal Myoblasts
Cardiomyopathies
Bone Marrow Cells
Heart Failure
Cell Transplantation
Treatment Failure
Regeneration
Fibrosis
Clinical Trials
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

これを引用

Miyagawa, Shigeru ; Matsumiya, Goro ; Funatsu, Toshihiro ; Yoshitatsu, Masao ; Sekiya, Naozumi ; Fukui, Shinya ; Hoashi, Takaya ; Hori, Masatsugu ; Yoshikawa, Hideki ; Kanakura, Yuzuru ; Ishikawa, Jun ; Aozasa, Katsuyuki ; Kawaguchi, Naomasa ; Matsuura, Nariaki ; Myoui, Akira ; Matsuyama, Akifumi ; Ezoe, Sachiko ; Iida, Hidehiro ; Matsuda, Hikaru ; Sawa, Yoshiki. / Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation : Report of a case. :: Surgery Today. 2009 ; 巻 39, 番号 2. pp. 133-136.
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Miyagawa, S, Matsumiya, G, Funatsu, T, Yoshitatsu, M, Sekiya, N, Fukui, S, Hoashi, T, Hori, M, Yoshikawa, H, Kanakura, Y, Ishikawa, J, Aozasa, K, Kawaguchi, N, Matsuura, N, Myoui, A, Matsuyama, A, Ezoe, S, Iida, H, Matsuda, H & Sawa, Y 2009, 'Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation: Report of a case', Surgery Today, 巻. 39, 番号 2, pp. 133-136. https://doi.org/10.1007/s00595-008-3803-x

Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation : Report of a case. / Miyagawa, Shigeru; Matsumiya, Goro; Funatsu, Toshihiro; Yoshitatsu, Masao; Sekiya, Naozumi; Fukui, Shinya; Hoashi, Takaya; Hori, Masatsugu; Yoshikawa, Hideki; Kanakura, Yuzuru; Ishikawa, Jun; Aozasa, Katsuyuki; Kawaguchi, Naomasa; Matsuura, Nariaki; Myoui, Akira; Matsuyama, Akifumi; Ezoe, Sachiko; Iida, Hidehiro; Matsuda, Hikaru; Sawa, Yoshiki.

:: Surgery Today, 巻 39, 番号 2, 01.02.2009, p. 133-136.

研究成果: Article

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AU - Yoshitatsu, Masao

AU - Sekiya, Naozumi

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AU - Hoashi, Takaya

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AU - Yoshikawa, Hideki

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AU - Myoui, Akira

AU - Matsuyama, Akifumi

AU - Ezoe, Sachiko

AU - Iida, Hidehiro

AU - Matsuda, Hikaru

AU - Sawa, Yoshiki

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