Comparative efficacy and acceptability of 3 repetitive transcranial magnetic stimulation devices for depression: A meta-analysis of randomized, sham-controlled trials

Yuki Matsuda, Ryuichi Yamazaki, Taro Kishi, Nakao Iwata, Masahiro Shigeta, Shinsuke Kito

研究成果: ジャーナルへの寄稿学術論文査読

抄録

Introduction: Repetitive transcranial magnetic stimulation (rTMS) has been employed worldwide for therapy-resistant depression. The Food and Drug Administration has approved a number of therapeutic devices for treating major depressive disorder; however, no studies have examined the differences in efficacy and acceptability among commercially available stimulation devices. The aim of our study was to compare the efficacy and acceptability of 3 stimulation devices (NeuroStar, MagPro, and Magstim) for depressive disorders. Methods: Our study included 31 randomized shamcontrolled trials of high-frequency rTMS included in the network meta-analysis by Brunoni. We calculated the risk ratio and 95% confidence intervals, comparing each device with sham for the endpoints of response rate, remission rate, and all-cause discontinuation. We then analyzed the differences among the devices in effect size for those endpoints. Results: After determining the effect sizes for the endpoints, we found no statistically significant subgroup differences in the response rates, all-cause discontinuation, or remission rates among the devices (p = 0.12, p = 0.84, and p = 0.07, respectively). Conclusion: Our results suggest similar efficacy and acceptability for the 3 stimulation devices. Future studies need to perform head-to-head comparisons of the efficacy and acceptability of the stimulation devices for treating depression using the same stimulation protocols.

本文言語英語
ページ(範囲)60-68
ページ数9
ジャーナルNeuropsychobiology
81
1
DOI
出版ステータス出版済み - 01-02-2022

All Science Journal Classification (ASJC) codes

  • 神経心理学および生理心理学
  • 精神医学および精神衛生
  • 生物学的精神医学

フィンガープリント

「Comparative efficacy and acceptability of 3 repetitive transcranial magnetic stimulation devices for depression: A meta-analysis of randomized, sham-controlled trials」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル