Comparative studies of asparagine-linked sugar chains of immunoglobulin G from eleven mammalian species

Jiharu Hamako, Taei Matsui, Yasuhiro Ozeki, Tsuguo Mizuochi, Koiti Titani

研究成果: Article査読

26 被引用数 (Scopus)

抄録

1. 1. Asparagine-linked sugar chains released by hydrazinolysis from IgGs of porcine, equine, bovine, goat, ovine, canine, rabbit, guinea-pig and rat were comparatively analyzed by microsequencing and lectin affinity chromatography. 2. 2. Sugar chains of all IgGs basically consisted of biantennary complex-type oligosaccharides containing 0-2 sialic acid residue(s). More than 70% of the oligosaccharides were neutral, except for guinea-pig IgG, and fucosylated trimannosyl core structures were dominant except for rabbit IgG. Bisecting N-acetylglucosamine residue was absent in porcine and equine IgGs. 3. 3. A large quantity of galactose-less oligosaccharides were present in IgGs of porcine, equine, canine and rat.

本文言語English
ページ(範囲)949-954
ページ数6
ジャーナルComparative Biochemistry and Physiology -- Part B: Biochemistry and
106
4
DOI
出版ステータスPublished - 12-1993

All Science Journal Classification (ASJC) codes

  • 生化学
  • 生理学
  • 分子生物学

フィンガープリント

「Comparative studies of asparagine-linked sugar chains of immunoglobulin G from eleven mammalian species」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル