Comparison of concentrations of Cry j 1 and Cry j 2 in diploid and triploid Japanese cedar (Cryptomeria japonica) pollen extracts

Y. Kondo, H. Ipsen, H. Løwenstein, A. Karpas, L. S. Hsieh

研究成果: Short survey査読

11 被引用数 (Scopus)

抄録

Japanese cedar (Cryptomeria japonica) pollinosis has been a serious allergic disease in Japan. There are two kinds of Japanese cedar trees; the popular one is diploid, the less popular is triploid. These trees are not very different morphologically. However, the relative allergenicity of their pollens is unknown, although both major allergens, Cry j 1 and Cry j 2, have been purified and cloned from the diploid line. Triploid trees are sterile and the allergenicity of their pollen may differ. Using Japanese-cedar- allergic patient sera, we compared the concentration of these two major allergens in both kinds of pollen. Pollen collected from different years and regions was also studied. The results indicate that triploid tree pollen extract has lower concentrations of both major allergens; therefore, the pollen may be less allergenic.

本文言語English
ページ(範囲)455-459
ページ数5
ジャーナルAllergy: European Journal of Allergy and Clinical Immunology
52
4
DOI
出版ステータスPublished - 1997

All Science Journal Classification (ASJC) codes

  • 免疫アレルギー学
  • 免疫学

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