Comparison of Severity of Viremia and Antibody Responses between Infants and Children with Measles

Sadao Suga, Tetsushi Yoshikawa, Yoshizo Asano, Toshihiko Nakashima, Takehiko Yazaki

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Severity of viremia and neutralizing antibody responses were compared between nine young infants ( 10 months) with measles and 18 infants and children ( 11 months) with ordinary measles. Peripheral blood mononuclear cell (PBMC)‐associated viremia was detected between the first day of elevation of fever (day 0) and day 5 of the disease in the former group, whereas PBMC‐associated and cell‐free viremia were detected between day 0 and day 14 in the latter group. The number of infected PBMC during the first 7 days of the disease was 3.22 ± 1.07 (log10, mean ± s.d.) per 10 million PBMC in the former group, which was significantly smaller (P= 0.02) than that of the latter group (4.21 ± 1.18). The former group reached the maximum level of antibody earlier than the latter group.

本文言語English
ページ(範囲)404-408
ページ数5
ジャーナルPediatrics International
34
4
DOI
出版ステータスPublished - 08-1992

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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