TY - JOUR
T1 - Contribution of the Nurses' Health Study to the Epidemiology of Cataract, Age-Related Macular Degeneration, and Glaucoma
AU - Kang, Jae H.
AU - Wu, Juan
AU - Cho, Eunyoung
AU - Ogata, Soshiro
AU - Jacques, Paul
AU - Taylor, Allen
AU - Chiu, Chung Jung
AU - Wiggs, Janey L.
AU - Seddon, Johanna M.
AU - Hankinson, Susan E.
AU - Schaumberg, Debra A.
AU - Pasquale, Louis R.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - OBJECTIVES: To review the contribution of the Nurses' Health Study (NHS) to understanding the genetic and lifestyle factors that influence the risk of cataract, age-related macular degeneration, and glaucoma.METHODS: We performed a narrative review of the publications of the NHS between 1976 and 2016.RESULTS: The NHS has helped to elucidate the roles of genetics, lifestyle factors (e.g., cigarette smoking associated with cataract extraction and age-related macular degeneration), medical conditions (e.g., diabetes associated with cataract extraction and glaucoma), and dietary factors (e.g., greater carotenoid intake and lower glycemic diet associated with lower risk of age-related macular degeneration) in the etiology of degree and progression of lens opacities, cataract extraction, age-related macular degeneration, primary open-angle glaucoma, and exfoliation glaucoma.CONCLUSIONS: The findings from the NHS, combined with those of other studies, have provided compelling evidence to support public health recommendations for helping to prevent age-related eye diseases: abstinence from cigarette smoking, maintenance of healthy weight and diabetes prevention, and a healthy diet rich in fruits and vegetables.
AB - OBJECTIVES: To review the contribution of the Nurses' Health Study (NHS) to understanding the genetic and lifestyle factors that influence the risk of cataract, age-related macular degeneration, and glaucoma.METHODS: We performed a narrative review of the publications of the NHS between 1976 and 2016.RESULTS: The NHS has helped to elucidate the roles of genetics, lifestyle factors (e.g., cigarette smoking associated with cataract extraction and age-related macular degeneration), medical conditions (e.g., diabetes associated with cataract extraction and glaucoma), and dietary factors (e.g., greater carotenoid intake and lower glycemic diet associated with lower risk of age-related macular degeneration) in the etiology of degree and progression of lens opacities, cataract extraction, age-related macular degeneration, primary open-angle glaucoma, and exfoliation glaucoma.CONCLUSIONS: The findings from the NHS, combined with those of other studies, have provided compelling evidence to support public health recommendations for helping to prevent age-related eye diseases: abstinence from cigarette smoking, maintenance of healthy weight and diabetes prevention, and a healthy diet rich in fruits and vegetables.
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U2 - 10.2105/AJPH.2016.303317
DO - 10.2105/AJPH.2016.303317
M3 - Review article
C2 - 27459452
AN - SCOPUS:84982123814
SN - 0090-0036
VL - 106
SP - 1684
EP - 1689
JO - American Journal of Public Health
JF - American Journal of Public Health
IS - 9
ER -
