Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae

Maria Fernanda C. Bueno, Gabriela R. Francisco, Jessica A. O'Hara, Doroti De Oliveira Garcia, Yohei Doi

研究成果: Article査読

63 被引用数 (Scopus)

抄録

Eight Klebsiella pneumoniae clinical strains with high-level aminoglycoside resistance were collected from eight hospitals in São Paulo State Brazil, in 2010 and 2011. Three of them produced an RmtD group 16S rRNA methyltransferase, RmtD1 or RmtD2. Five strains were found to produce a novel 16S rRNA methyltransferase, designated RmtG, which shared 57 to 58% amino acid identity with RmtD1 and RmtD2. Seven strains coproduced KPC-2 with or without various CTX-M group extended-spectrum βlactamases, while the remaining strain coproduced CTX-M-2.

本文言語English
ページ(範囲)2397-2400
ページ数4
ジャーナルAntimicrobial agents and chemotherapy
57
5
DOI
出版ステータスPublished - 05-2013

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

フィンガープリント 「Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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