Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae

Maria Fernanda C. Bueno; Gabriela R. Francisco; Jessica A. O'Hara; Doroti De Oliveira Garcia; Yohei Doi

doi:10.1128/AAC.02108-12

Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae

Maria Fernanda C. Bueno
, Gabriela R. Francisco
, Jessica A. O'Hara
, Doroti De Oliveira Garcia
, Yohei Doi

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

88 被引用数 (Scopus)

抄録

Eight Klebsiella pneumoniae clinical strains with high-level aminoglycoside resistance were collected from eight hospitals in São Paulo State Brazil, in 2010 and 2011. Three of them produced an RmtD group 16S rRNA methyltransferase, RmtD1 or RmtD2. Five strains were found to produce a novel 16S rRNA methyltransferase, designated RmtG, which shared 57 to 58% amino acid identity with RmtD1 and RmtD2. Seven strains coproduced KPC-2 with or without various CTX-M group extended-spectrum βlactamases, while the remaining strain coproduced CTX-M-2.

本文言語	英語
ページ（範囲）	2397-2400
ページ数	4
ジャーナル	Antimicrobial agents and chemotherapy
巻	57
号	5
DOI	https://doi.org/10.1128/AAC.02108-12
出版ステータス	出版済み - 05-2013
外部発表	はい

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All Science Journal Classification (ASJC) codes

薬理学
薬理学（医学）
感染症

文献へのアクセス

10.1128/AAC.02108-12

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「Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

@article{ada8d2c9d61f433f9ae967cfcbaf44d5,

title = "Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae",

abstract = "Eight Klebsiella pneumoniae clinical strains with high-level aminoglycoside resistance were collected from eight hospitals in S{\~a}o Paulo State Brazil, in 2010 and 2011. Three of them produced an RmtD group 16S rRNA methyltransferase, RmtD1 or RmtD2. Five strains were found to produce a novel 16S rRNA methyltransferase, designated RmtG, which shared 57 to 58\% amino acid identity with RmtD1 and RmtD2. Seven strains coproduced KPC-2 with or without various CTX-M group extended-spectrum βlactamases, while the remaining strain coproduced CTX-M-2.",

author = "Bueno, \{Maria Fernanda C.\} and Francisco, \{Gabriela R.\} and O'Hara, \{Jessica A.\} and \{De Oliveira Garcia\}, Doroti and Yohei Doi",

year = "2013",

month = may,

doi = "10.1128/AAC.02108-12",

language = "English",

volume = "57",

pages = "2397--2400",

journal = "Antimicrobial agents and chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "5",

}

Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae. / Bueno, Maria Fernanda C.; Francisco, Gabriela R.; O'Hara, Jessica A. その他.
In: Antimicrobial agents and chemotherapy, Vol. 57, No. 5, 05.2013, p. 2397-2400.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

TY - JOUR

T1 - Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum βlactamases in Klebsiella pneumoniae

AU - Bueno, Maria Fernanda C.

AU - Francisco, Gabriela R.

AU - O'Hara, Jessica A.

AU - De Oliveira Garcia, Doroti

AU - Doi, Yohei

PY - 2013/5

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AB - Eight Klebsiella pneumoniae clinical strains with high-level aminoglycoside resistance were collected from eight hospitals in São Paulo State Brazil, in 2010 and 2011. Three of them produced an RmtD group 16S rRNA methyltransferase, RmtD1 or RmtD2. Five strains were found to produce a novel 16S rRNA methyltransferase, designated RmtG, which shared 57 to 58% amino acid identity with RmtD1 and RmtD2. Seven strains coproduced KPC-2 with or without various CTX-M group extended-spectrum βlactamases, while the remaining strain coproduced CTX-M-2.

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