De novo spinal teratoma after treatment of an intracranial germ cell tumor

Yasuo Tohma, Takuro Kaneko, Daisuke Kita, Masayuki Iwato, Yutaka Hayashi, Osamu Tachibana, Mitsuhiro Hasegawa, Junkoh Yamashita

研究成果: Article査読

5 被引用数 (Scopus)

抄録

The authors report an extremely rare case of de novo spinal teratoma after treatment for intracranial germ cell tumor. A 17-year-old male developed pain of bilateral lower extremities and urinary retention 18 months after complete remission of intracranial mixed germ cell tumor. Magnetic resonance imaging revealed a huge spinal tumor associated with spina bifida occulta. Total resection was performed, and histogenetical findings led to the diagnosis of a mature teratoma with normal p16 gene, whereas analysis of intracranial tumor showed p16 deletion. The spinal anomaly and genetic analysis strongly suggest that the spinal teratoma was a de novo tumor rather than a metastasis or dissemination of the original intracranial germ cell tumor.

本文言語English
ページ(範囲)261-264
ページ数4
ジャーナルPediatric Neurosurgery
33
5
DOI
出版ステータスPublished - 01-12-2000
外部発表はい

All Science Journal Classification (ASJC) codes

  • 小児科学、周産期医学および子どもの健康
  • 外科
  • 臨床神経学

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