Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector

T. Nabeshima; M. Hiramatsu; S. Noma; M. Ukai; M. Amano; T. Kameyama

Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector

T. Nabeshima, M. Hiramatsu, S. Noma, M. Ukai, M. Amano, T. Kameyama

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

抄録

High-pressure liquid chromatography with electrochemical detection is utilized in a procedure for the determination of methionine-enkephalin (MET-ENK), norepinephrine (NE), dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) is same brain tissue samples. The high degree of selectivity and sensitivity (picomole limits for each component) makes this technique directly applicable to extremely small samples. After optimal conditions had been established, the procedure was employed in the determination of MET-ENK, NE, DA, DOPAC and HVA contents in whole brains, 7 discrete brain areas of mice and rats.

本文言語	英語
ページ（範囲）	421-442
ページ数	22
ジャーナル	Research Communications in Chemical Pathology and Pharmacology
巻	35
号	3
出版ステータス	出版済み - 1982
外部発表	はい

All Science Journal Classification (ASJC) codes

薬理学、毒性学および薬学一般
病理学および法医学
毒物学
薬理学

他のファイルとリンク

フィンガープリント

「Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

Nabeshima, T., Hiramatsu, M., Noma, S., Ukai, M., Amano, M., & Kameyama, T. (1982). Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector. Research Communications in Chemical Pathology and Pharmacology, 35(3), 421-442.

Nabeshima, T. ; Hiramatsu, M. ; Noma, S. その他. / Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector. In: Research Communications in Chemical Pathology and Pharmacology. 1982 ; Vol. 35, No. 3. pp. 421-442.

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title = "Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector",

abstract = "High-pressure liquid chromatography with electrochemical detection is utilized in a procedure for the determination of methionine-enkephalin (MET-ENK), norepinephrine (NE), dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) is same brain tissue samples. The high degree of selectivity and sensitivity (picomole limits for each component) makes this technique directly applicable to extremely small samples. After optimal conditions had been established, the procedure was employed in the determination of MET-ENK, NE, DA, DOPAC and HVA contents in whole brains, 7 discrete brain areas of mice and rats.",

author = "T. Nabeshima and M. Hiramatsu and S. Noma and M. Ukai and M. Amano and T. Kameyama",

year = "1982",

language = "English",

volume = "35",

pages = "421--442",

journal = "Research Communications in Chemical Pathology and Pharmacology",

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Nabeshima, T, Hiramatsu, M, Noma, S, Ukai, M, Amano, M & Kameyama, T 1982, 'Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector', Research Communications in Chemical Pathology and Pharmacology, vol. 35, no. 3, pp. 421-442.

Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector. / Nabeshima, T.; Hiramatsu, M.; Noma, S. その他.
In: Research Communications in Chemical Pathology and Pharmacology, Vol. 35, No. 3, 1982, p. 421-442.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

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Nabeshima T, Hiramatsu M, Noma S, Ukai M, Amano M, Kameyama T. Determination of methionine-enkephalin, norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxy-4-hydroxyphenylacetic acid (HVA) in brain by high-pressure liquid chromatography with electrochemical detector. Research Communications in Chemical Pathology and Pharmacology. 1982;35(3):421-442.