Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women

Ehab S. Eshak, Hiroyasu Iso, Chigusa Date, Shogo Kikuchi, Yoshiyuki Watanabe, Yasuhiko Wada, Kenji Wakai, Akiko Tamakoshi, Mitsuru Mori, Fumio Sakauchi, Yutaka Motohashi, Ichiro Tsuji, Yosikazu Nakamura, Haruo Mikami, Michiko Kurosawa, Yoshiharu Hoshiyama, Naohito Tanabe, Koji Tamakoshi, Shinkan Tokudome, Koji SuzukiShuji Hashimoto, Takashi Kawamura, Kotarou Ozasa, Tsuneharu Miki, Kiyomi Sakata, Takesumi Yoshimura, Yoshihisa Fujino, Akira Shibata, Naoyuki Okamoto, Hideo Shio

研究成果: Article

90 引用 (Scopus)

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Dietary fiber protects against coronary heart disease (CHD), but evidence in Asia is limited. We examined the association between dietary fiber intake and mortality from cardiovascular disease (CVD) in a Japanese population in a prospective study of 58,730 Japanesemen andwomenaged 40-79 y in which dietary fiber intake was determined by a self-administered FFQ. The participants were followed up from 1988-1990 to the end of 2003. Hazard ratios (HR) and 95% CI of mortality were calculated per quintile of fiber intake. During the 14-y follow-up, a total of 2080 CVD deaths (983 strokes, 422 CHD, and 675 other CVD) were documented. Total, insoluble, and soluble dietary fiber intakes were inversely associated with risk of mortality from CHD and total CVD for both men and women. For men, the multivariable HR (95% CI) for CHD in the highest vs. the lowest quintiles were 0.81 [(95% CI, 0.61-1.09); P-trend = 0.02], 0.48 [(95% CI, 0.27-0.84); P-trend < 0.001], and 0.71 [(95% CI, 0.41-0.97); P-trend = 0.04] for total, insoluble, and soluble fiber, respectively. The respective HR (95% CI) for women were 0.80 [(95% CI, 0.57-0.97); P-trend = 0.01], 0.49 [(95% CI, 0.27-0.86); P-trend = 0.004], and 0.72 [(95% CI, 0.34-0.99); P-trend = 0.03], respectively. For fiber sources, intakes of fruit and cereal fibers but not vegetable fiber were inversely associated with risk of mortality from CHD. In conclusion, dietary intakes of fiber, both insoluble and soluble fibers, and especially fruit and cereal fibers, may reduce risk of mortality from CHD.

元の言語English
ページ(範囲)1445-1453
ページ数9
ジャーナルJournal of Nutrition
140
発行部数8
DOI
出版物ステータスPublished - 01-08-2010

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All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

これを引用

Eshak, E. S., Iso, H., Date, C., Kikuchi, S., Watanabe, Y., Wada, Y., Wakai, K., Tamakoshi, A., Mori, M., Sakauchi, F., Motohashi, Y., Tsuji, I., Nakamura, Y., Mikami, H., Kurosawa, M., Hoshiyama, Y., Tanabe, N., Tamakoshi, K., Tokudome, S., ... Shio, H. (2010). Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women. Journal of Nutrition, 140(8), 1445-1453. https://doi.org/10.3945/jn.110.122358