TY - JOUR
T1 - Does quazepam influence sleep and daytime activity in healthy adults?
AU - Kusunoki, Kazunori
AU - Kitajima, Tsuyoshi
AU - Ozaki, Norio
N1 - Publisher Copyright:
© 2003, Japanese Society of Sleep Research.
PY - 2003/3/1
Y1 - 2003/3/1
N2 - A pilot study using actigraph was conducted to assess the effects of a 1-week repeated administration of 15 mg of quazepam on the sleep and daytime activity of six healthy adults. The nocturnal sleep time gradually increased during quazepam administration, and a significant difference from the baseline was noted on the seventh day of administration. There was no significant difference in the daytime activity before and after the administration. Quazepam and its active metabolites appear to have acted on the level not affecting the daytime activity but prolonging the nocturnal sleep time through their interactions.
AB - A pilot study using actigraph was conducted to assess the effects of a 1-week repeated administration of 15 mg of quazepam on the sleep and daytime activity of six healthy adults. The nocturnal sleep time gradually increased during quazepam administration, and a significant difference from the baseline was noted on the seventh day of administration. There was no significant difference in the daytime activity before and after the administration. Quazepam and its active metabolites appear to have acted on the level not affecting the daytime activity but prolonging the nocturnal sleep time through their interactions.
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U2 - 10.1046/j.1446-9235.2003.00036.x
DO - 10.1046/j.1446-9235.2003.00036.x
M3 - Article
AN - SCOPUS:84979948935
SN - 1446-9235
VL - 1
SP - 171
EP - 172
JO - Sleep and Biological Rhythms
JF - Sleep and Biological Rhythms
IS - 2
ER -