Dynamic MR imaging: Value of differentiating subtypes of peripheral small adenocarcinoma of the lung

Yoshiharu Ohno, Hiroto Hatabu, Daisuke Takenaka, Hidemasa Uematsu, Chiho Ohbayashi, Takanori Higashino, Munenobu Nogami, Masahiro Yoshimura, Masahiko Fujii, Kazuro Sugimura

研究成果: Article

37 引用 (Scopus)

抜粋

Purpose: To determine the utility of dynamic magnetic resonance imaging (MRI) in the differential subtyping of small adenocarcinomas of the lung. Materials and methods: Twenty-nine pathologically diagnosed peripheral adenocarcinomas (less than 20 mm in diameter) underwent dynamic contrast-enhanced MRI. Maximum relative enhancement ratio, slope of enhancement, and corrected start time of enhancement were calculated from signal intensity-time curve of pulmonary lesion for each subject, and were statistically compared among bronchioloalveolar carcinoma (BAC) group (7 cases), mixed BAC group (10 cases), and adenocarcinoma group (12 cases). Results: Maximum relative enhancement ratio (P<0.001) and slope of enhancement (P<0.001) of BAC group were significantly higher than those of mixed BAC and adenocarcinoma groups. Start times of BAC group were significantly earlier than those of mixed BAC (P=0.0001) and adenocarcinoma groups (P<0.0001). Adapting the thresholds values of MR indexes from the positive tests, sensitivity, specificity, positive predictive value, negative predictive value and accuracy for differentiating BAC from other subtypes were 85.7, 100.0, 100.0, 95.7, and 96.6%, respectively. Conclusions: Dynamic MRI is useful for differentiating subtypes of small peripheral adenocarcinoma.

元の言語English
ページ(範囲)144-150
ページ数7
ジャーナルEuropean journal of radiology
52
発行部数2
DOI
出版物ステータスPublished - 11-2004

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

フィンガープリント Dynamic MR imaging: Value of differentiating subtypes of peripheral small adenocarcinoma of the lung' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Ohno, Y., Hatabu, H., Takenaka, D., Uematsu, H., Ohbayashi, C., Higashino, T., Nogami, M., Yoshimura, M., Fujii, M., & Sugimura, K. (2004). Dynamic MR imaging: Value of differentiating subtypes of peripheral small adenocarcinoma of the lung. European journal of radiology, 52(2), 144-150. https://doi.org/10.1016/j.ejrad.2004.01.015