Eating fast leads to insulin resistance: Findings in middle-aged Japanese men and women

Rei Otsuka, Koji Tamakoshi, Hiroshi Yatsuya, Keiko Wada, Kunihiro Matsushita, Pei OuYang, Yo Hotta, Seiko Takefuji, Hirotsugu Mitsuhashi, Kaichiro Sugiura, Satoshi Sasaki, John G. Kral, Hideaki Toyoshima

研究成果: Article査読

79 被引用数 (Scopus)


Objective: To examine relationships between speed of eating and insulin resistance. Methods: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m2) and 761 female (46.3 y and 21.8 kg/m2) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). Results: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p < 0.001, for trend) and in women (p < 0.01). Adjusting for BMI, this positive relationship appeared only in men (p = 0.03). Conclusions: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.

ジャーナルPreventive Medicine
出版ステータスPublished - 02-2008

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Public Health, Environmental and Occupational Health

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