Effect of transmucosal fluid movement on zinc and copper absorption from the rat small intestine

Takafumi Kuzuya, Takaaki Hasegawa, Yozo Ogura, Toshitaka Nabeshima

研究成果: Article査読

7 被引用数 (Scopus)

抄録

1. The effects of transmucosal fluid movement on zinc and Copper absorption from rat small intestine were investigated using an in recirculating perfusion method. 2. Transmucosal fluid movement was obtained by using hypo-, iso- or hyperosmotic perfusate containing various concentrations of sodium chloride. Linear correlations were obtained between net fluid movement and absorption rate constants, which were calculated from the perfusion decline of zinc (n = 15; r = 0.77) and copper (n = 15; r = 0.75). 3. The changes in serum levels of these metals did not correlate with the increase in the absorption rate. 4. The present study indicates that zinc and copper absorption is dependent on transmucosal fluid movement.

本文言語English
ページ(範囲)412-416
ページ数5
ジャーナルClinical and Experimental Pharmacology and Physiology
25
6
DOI
出版ステータスPublished - 01-01-1998
外部発表はい

All Science Journal Classification (ASJC) codes

  • Physiology
  • Pharmacology
  • Physiology (medical)

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