Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan

Takeshi Arashiro; Yuzo Arima; Jin Kuramochi; Hirokazu Muraoka; Akihiro Sato; Kumi Chubachi; Atsushi Yanai; Hiroko Arioka; Yuki Uehara; Genei Ihara; Yasuyuki Kato; Naoki Yanagisawa; Akihiro Ueda; Hideaki Kato; Hideaki Oka; Yusuke Nishida; Yuki Nidaira; Takahiro Asami; Torahiko Jinta; Akira Nakamura; Kunihiro Oba; Daisuke Taniyama; Kei Yamamoto; Katsushi Tanaka; Kankuro Ueshima; Tetsuji Fuwa; Ashley Stucky; Tadaki Suzuki; Chris Smith; Martin Hibberd; Koya Ariyoshi; Motoi Suzuki

doi:10.1093/ofid/ofad240

Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan

Takeshi Arashiro, Yuzo Arima, Jin Kuramochi, Hirokazu Muraoka, Akihiro Sato, Kumi Chubachi, Atsushi Yanai, Hiroko Arioka, Yuki Uehara, Genei Ihara, Yasuyuki Kato, Naoki Yanagisawa, Akihiro Ueda, Hideaki Kato, Hideaki Oka, Yusuke Nishida, Yuki Nidaira, Takahiro Asami, Torahiko Jinta, Akira NakamuraKunihiro Oba, Daisuke Taniyama, Kei Yamamoto, Katsushi Tanaka, Kankuro Ueshima, Tetsuji Fuwa, Ashley Stucky, Tadaki Suzuki, Chris Smith, Martin Hibberd, Koya Ariyoshi, Motoi Suzuki

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

抄録

In this multicenter, prospective, test-negative, case-control study in Japan, the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent coronavirus disease 2019 mRNA vaccines against symptomatic infection during the BA.5-dominant period was high compared with no vaccination (65% and 76%) and moderate compared with monovalent vaccines administered over half a year earlier (46% combined).

本文言語	英語
論文番号	ofad240
ジャーナル	Open Forum Infectious Diseases
巻	10
号	6
DOI	https://doi.org/10.1093/ofid/ofad240
出版ステータス	出版済み - 01-06-2023
外部発表	はい

All Science Journal Classification (ASJC) codes

腫瘍学
感染症

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1093/ofid/ofad240

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フィンガープリント

「Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

Arashiro, T., Arima, Y., Kuramochi, J., Muraoka, H., Sato, A., Chubachi, K., Yanai, A., Arioka, H., Uehara, Y., Ihara, G., Kato, Y., Yanagisawa, N., Ueda, A., Kato, H., Oka, H., Nishida, Y., Nidaira, Y., Asami, T., Jinta, T., ... Suzuki, M. (2023). Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan. Open Forum Infectious Diseases, 10(6), 記事 ofad240. https://doi.org/10.1093/ofid/ofad240

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title = "Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan",

abstract = "In this multicenter, prospective, test-negative, case-control study in Japan, the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent coronavirus disease 2019 mRNA vaccines against symptomatic infection during the BA.5-dominant period was high compared with no vaccination (65% and 76%) and moderate compared with monovalent vaccines administered over half a year earlier (46% combined).",

keywords = "COVID-19, SARS-CoV-2, SARS-CoV-2 variants, test-negative design, vaccine effectiveness",

author = "Takeshi Arashiro and Yuzo Arima and Jin Kuramochi and Hirokazu Muraoka and Akihiro Sato and Kumi Chubachi and Atsushi Yanai and Hiroko Arioka and Yuki Uehara and Genei Ihara and Yasuyuki Kato and Naoki Yanagisawa and Akihiro Ueda and Hideaki Kato and Hideaki Oka and Yusuke Nishida and Yuki Nidaira and Takahiro Asami and Torahiko Jinta and Akira Nakamura and Kunihiro Oba and Daisuke Taniyama and Kei Yamamoto and Katsushi Tanaka and Kankuro Ueshima and Tetsuji Fuwa and Ashley Stucky and Tadaki Suzuki and Chris Smith and Martin Hibberd and Koya Ariyoshi and Motoi Suzuki",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.",

year = "2023",

month = jun,

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doi = "10.1093/ofid/ofad240",

language = "English",

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Arashiro, T, Arima, Y, Kuramochi, J, Muraoka, H, Sato, A, Chubachi, K, Yanai, A, Arioka, H, Uehara, Y, Ihara, G, Kato, Y, Yanagisawa, N, Ueda, A, Kato, H, Oka, H, Nishida, Y, Nidaira, Y, Asami, T, Jinta, T, Nakamura, A, Oba, K, Taniyama, D, Yamamoto, K, Tanaka, K, Ueshima, K, Fuwa, T, Stucky, A, Suzuki, T, Smith, C, Hibberd, M, Ariyoshi, K & Suzuki, M 2023, 'Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan', Open Forum Infectious Diseases, vol. 10, no. 6, ofad240. https://doi.org/10.1093/ofid/ofad240

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T1 - Effectiveness of BA.1- and BA.4/BA. 5-Containing Bivalent COVID-19 mRNA Vaccines Against Symptomatic SARS-CoV-2 Infection During the BA.5-Dominant Period in Japan

AU - Arashiro, Takeshi

AU - Arima, Yuzo

AU - Kuramochi, Jin

AU - Muraoka, Hirokazu

AU - Sato, Akihiro

AU - Chubachi, Kumi

AU - Yanai, Atsushi

AU - Arioka, Hiroko

AU - Uehara, Yuki

AU - Ihara, Genei

AU - Kato, Yasuyuki

AU - Yanagisawa, Naoki

AU - Ueda, Akihiro

AU - Kato, Hideaki

AU - Oka, Hideaki

AU - Nishida, Yusuke

AU - Nidaira, Yuki

AU - Asami, Takahiro

AU - Jinta, Torahiko

AU - Nakamura, Akira

AU - Oba, Kunihiro

AU - Taniyama, Daisuke

AU - Yamamoto, Kei

AU - Tanaka, Katsushi

AU - Ueshima, Kankuro

AU - Fuwa, Tetsuji

AU - Stucky, Ashley

AU - Suzuki, Tadaki

AU - Smith, Chris

AU - Hibberd, Martin

AU - Ariyoshi, Koya

AU - Suzuki, Motoi

PY - 2023/6/1

Y1 - 2023/6/1

N2 - In this multicenter, prospective, test-negative, case-control study in Japan, the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent coronavirus disease 2019 mRNA vaccines against symptomatic infection during the BA.5-dominant period was high compared with no vaccination (65% and 76%) and moderate compared with monovalent vaccines administered over half a year earlier (46% combined).

AB - In this multicenter, prospective, test-negative, case-control study in Japan, the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent coronavirus disease 2019 mRNA vaccines against symptomatic infection during the BA.5-dominant period was high compared with no vaccination (65% and 76%) and moderate compared with monovalent vaccines administered over half a year earlier (46% combined).

KW - COVID-19

KW - SARS-CoV-2

KW - SARS-CoV-2 variants

KW - test-negative design

KW - vaccine effectiveness

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DO - 10.1093/ofid/ofad240

M3 - Article

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SN - 2328-8957

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