Effects of Constant Intake of Lutein-rich Spinach on Macular Pigment Optical Density: a Pilot Study

Yoko Ozawa; Norihiro Nagai; Misa Suzuki; Toshihide Kurihara; Hajime Shinoda; Mitsuru Watanabe; Kazuo Tsubota

Effects of Constant Intake of Lutein-rich Spinach on Macular Pigment Optical Density: a Pilot Study

Yoko Ozawa
, Norihiro Nagai
, Misa Suzuki
, Toshihide Kurihara
, Hajime Shinoda
, Mitsuru Watanabe
, Kazuo Tsubota

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

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RESULTS: Mean lutein ± SD intake from food was 0.87 ± 0.76 mg/1,000 kcal at baseline. Mean MPOD, best corrected visual acuity, and serum lutein concentrations were increased at 1 and 2 months compared with baseline.

CONCLUSION: Constant intake of lutein-rich spinach increased both MPOD and serum lutein concentrations. These data are important for planning of a future interventional study examining the effects of dietary lutein.

PURPOSE: Anti-oxidative nutrient supplements, including lutein, are an important preventive approach for age-related macular degeneration (AMD). In this pilot study, we obtained data required for planning a future dietary intervention study investigating the prevention of AMD progression with lutein-rich spinach.

METHODS: We examined 22 eyes from 11 healthy nonsmokers (ages 21-45 years) who ingested 75 g of frozen spinach containing 10 mg lutein every day for 2 months. Food frequency questionnaire, measurement of macular pigment optical density (MPOD), and eye and blood examinations were performed.

本文言語	英語
ページ（範囲）	41-48
ページ数	8
ジャーナル	Nippon Ganka Gakkai zasshi
巻	120
号	1
出版ステータス	出版済み - 01-01-2016
外部発表	はい

All Science Journal Classification (ASJC) codes

医学一般

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title = "Effects of Constant Intake of Lutein-rich Spinach on Macular Pigment Optical Density: a Pilot Study",

abstract = "RESULTS: Mean lutein ± SD intake from food was 0.87 ± 0.76 mg/1,000 kcal at baseline. Mean MPOD, best corrected visual acuity, and serum lutein concentrations were increased at 1 and 2 months compared with baseline.CONCLUSION: Constant intake of lutein-rich spinach increased both MPOD and serum lutein concentrations. These data are important for planning of a future interventional study examining the effects of dietary lutein.PURPOSE: Anti-oxidative nutrient supplements, including lutein, are an important preventive approach for age-related macular degeneration (AMD). In this pilot study, we obtained data required for planning a future dietary intervention study investigating the prevention of AMD progression with lutein-rich spinach.METHODS: We examined 22 eyes from 11 healthy nonsmokers (ages 21-45 years) who ingested 75 g of frozen spinach containing 10 mg lutein every day for 2 months. Food frequency questionnaire, measurement of macular pigment optical density (MPOD), and eye and blood examinations were performed.",

author = "Yoko Ozawa and Norihiro Nagai and Misa Suzuki and Toshihide Kurihara and Hajime Shinoda and Mitsuru Watanabe and Kazuo Tsubota",

year = "2016",

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T1 - Effects of Constant Intake of Lutein-rich Spinach on Macular Pigment Optical Density

T2 - a Pilot Study

AU - Ozawa, Yoko

AU - Nagai, Norihiro

AU - Suzuki, Misa

AU - Kurihara, Toshihide

AU - Shinoda, Hajime

AU - Watanabe, Mitsuru

AU - Tsubota, Kazuo

PY - 2016/1/1

Y1 - 2016/1/1

N2 - RESULTS: Mean lutein ± SD intake from food was 0.87 ± 0.76 mg/1,000 kcal at baseline. Mean MPOD, best corrected visual acuity, and serum lutein concentrations were increased at 1 and 2 months compared with baseline.CONCLUSION: Constant intake of lutein-rich spinach increased both MPOD and serum lutein concentrations. These data are important for planning of a future interventional study examining the effects of dietary lutein.PURPOSE: Anti-oxidative nutrient supplements, including lutein, are an important preventive approach for age-related macular degeneration (AMD). In this pilot study, we obtained data required for planning a future dietary intervention study investigating the prevention of AMD progression with lutein-rich spinach.METHODS: We examined 22 eyes from 11 healthy nonsmokers (ages 21-45 years) who ingested 75 g of frozen spinach containing 10 mg lutein every day for 2 months. Food frequency questionnaire, measurement of macular pigment optical density (MPOD), and eye and blood examinations were performed.

AB - RESULTS: Mean lutein ± SD intake from food was 0.87 ± 0.76 mg/1,000 kcal at baseline. Mean MPOD, best corrected visual acuity, and serum lutein concentrations were increased at 1 and 2 months compared with baseline.CONCLUSION: Constant intake of lutein-rich spinach increased both MPOD and serum lutein concentrations. These data are important for planning of a future interventional study examining the effects of dietary lutein.PURPOSE: Anti-oxidative nutrient supplements, including lutein, are an important preventive approach for age-related macular degeneration (AMD). In this pilot study, we obtained data required for planning a future dietary intervention study investigating the prevention of AMD progression with lutein-rich spinach.METHODS: We examined 22 eyes from 11 healthy nonsmokers (ages 21-45 years) who ingested 75 g of frozen spinach containing 10 mg lutein every day for 2 months. Food frequency questionnaire, measurement of macular pigment optical density (MPOD), and eye and blood examinations were performed.

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AN - SCOPUS:84979850697

SN - 0029-0203

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JO - Nippon Ganka Gakkai zasshi

JF - Nippon Ganka Gakkai zasshi

IS - 1

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Effects of Constant Intake of Lutein-rich Spinach on Macular Pigment Optical Density: a Pilot Study

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