Effects of rapid random flash stimuli on electroretinographic responses

The effects of rapid random flash stimuli on electroretinographic (ERG) responses were studied in a normal eye. The subject was fitted with contact lenses with built-in light-emitting diode and recording electrodes. Comparison of first-order kernels of ERG elicited by binary m-sequence flashes with conventional flash ERG responses showed that without enough background illumination, high luminance rapid random stimuli produced first- order kernel responses with short implicit times similar to those of flash cone ERG responses. This result suggests that high luminance rapid random stimuli can cause light adaptation.