Effects of water temperature and weight of wheel load on water wheel turning behavior of imipramine administered mice

Jun Shimizu, Soichiro Nomura, Hiroko Kuno, Tsuneyuki Nakazawa

研究成果: Article査読

10 被引用数 (Scopus)

抄録

This experiment investigated the effect of imipramine on water wheel turning behavior in relation to the water temperature and the wheel load. It was shown that the higher the water temperature, the more the mice rotated the wheel, and the greater the wheel load, the less mice rotated it. However, these factors did not reduce the effect of imipramine, which increased the number of responses. It was suggested that the water wheel test shows promise as a screening test for antidepressants.

本文言語English
ページ(範囲)20-21
ページ数2
ジャーナルPsychopharmacology
84
1
DOI
出版ステータスPublished - 09-1984
外部発表はい

All Science Journal Classification (ASJC) codes

  • 薬理学

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