Efficacy of the BioBox LAB10 for maintaining temperature and quality of packed red blood cells during in-hospital storage and transport

Background: Packed red blood cells (PRBC) are stored at 2°C–6°C to ensure quality. Improper temperature control during PRBC transport reduces the quality of downstream blood products and wastes PRBC units. This study evaluated the suitability of the BioBox LAB10 for in-hospital PRBC transport. Methods: Temperatures of the box interior and simulated formulation were measured to assess cooling capabilities. Quality was evaluated by measuring red blood cell count, haemoglobin concentration, haematocrit, pH, potassium concentration, and ATP concentration of PRBC samples. The storage capacity, size, weight, and cost of the BioBox was compared with that of the ATR700. Results: The BioBox cooled to ≤6°C within 14 min. PRBC temperature remained ≤6°C for approximately 19 h. None of the quality parameters, including ATP concentration, differed significantly between samples stored in the BioBox or in a refrigerator. The BioBox is smaller, lighter, and 84% less expensive than the ATR700, with an equivalent storage capacity. Conclusions: The BioBox effectively maintains temperature and PRBC quality during transport and provides a practical solution for in-hospital transport of blood for transfusion owing to its compact, lightweight design, and affordability.