Engrailed and tectum development

Minoru Omi, Harukazu Nakamura

研究成果: Review article査読

3 被引用数 (Scopus)

抄録

The optic tectum is a visual center of nonmammalian vertebrates derived from the mesencephalon. In this review, function of Engrailed (En) in tectum development is reviewed. En plays crucial roles at three steps of tectum development. First, Engrailed is expressed in the mesencephalon and the metencephalon and essential for the regionalization of the mesencephalon. En is expressed in a gradient of caudal-to-rostral in the tectum primordial, and regulates the rostrocaudal polarity of the tectum. In the advanced stage of tectum development, En is expressed in a lamina-specific manner and it is suggested that En regulates cell migration in the tectal laminar formation.

本文言語English
ページ(範囲)135-145
ページ数11
ジャーナルDevelopment Growth and Differentiation
57
2
DOI
出版ステータスPublished - 01-02-2015
外部発表はい

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

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