Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

Tsuyoshi Miyakawa; Takeshi Yagi; Masahiko Taniguchi; Hiroaki Matsuura; Kyoko Tateishi; Hiroaki Niki

doi:10.1016/0169-328X(94)00251-9

Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

Tsuyoshi Miyakawa
, Takeshi Yagi
, Masahiko Taniguchi
, Hiroaki Matsuura
, Kyoko Tateishi
, Hiroaki Niki

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

45 被引用数 (Scopus)

抄録

Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fyn^z fyn^z) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

本文言語	英語
ページ（範囲）	349-352
ページ数	4
ジャーナル	Molecular Brain Research
巻	28
号	2
DOI	https://doi.org/10.1016/0169-328X(94)00251-9
出版ステータス	出版済み - 02-1995
外部発表	はい

All Science Journal Classification (ASJC) codes

分子生物学
細胞および分子神経科学

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10.1016/0169-328X(94)00251-9

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title = "Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice",

abstract = "Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.",

author = "Tsuyoshi Miyakawa and Takeshi Yagi and Masahiko Taniguchi and Hiroaki Matsuura and Kyoko Tateishi and Hiroaki Niki",

year = "1995",

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AU - Miyakawa, Tsuyoshi

AU - Yagi, Takeshi

AU - Taniguchi, Masahiko

AU - Matsuura, Hiroaki

AU - Tateishi, Kyoko

AU - Niki, Hiroaki

PY - 1995/2

Y1 - 1995/2

N2 - Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

AB - Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

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U2 - 10.1016/0169-328X(94)00251-9

DO - 10.1016/0169-328X(94)00251-9

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AN - SCOPUS:0028895999

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Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

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All Science Journal Classification (ASJC) codes

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