Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients

Jun Kunizaki; Shiro Sugiura; Akira Sakai; Miyuki Teshigawara; Atsushi Makino; Yoshihiro Takasato; Teruaki Matsui; Yasuto Kondo; Komei Ito

doi:10.3389/falgy.2023.1298137

Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients

Jun Kunizaki
, Shiro Sugiura
, Akira Sakai
, Miyuki Teshigawara
, Atsushi Makino
, Yoshihiro Takasato
, Teruaki Matsui
, Yasuto Kondo
, Komei Ito

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

抄録

Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose EIARD. EPT was performed on 20 participants, and in vivo basophil activation status was analyzed using activation markers CD203c and CD63. The results showed that there was no significant difference between EPT-positive and negative subjects for basophil activation status throughout EPT. Consequently, in vivo basophil activation after ingestion of the causative food may not be associated with EIARDs. New tests are desired for predicting EIARDs.

本文言語	英語
論文番号	1298137
ジャーナル	Frontiers in Allergy
巻	4
DOI	https://doi.org/10.3389/falgy.2023.1298137
出版ステータス	出版済み - 2023
外部発表	はい

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

SDG 3 すべての人に健康と福祉を

All Science Journal Classification (ASJC) codes

免疫アレルギー学
感染症

文献へのアクセス

10.3389/falgy.2023.1298137

他のファイルとリンク

引用スタイル

@article{7893775acdcb454686160b9fc0316176,

title = "Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients",

abstract = "Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose EIARD. EPT was performed on 20 participants, and in vivo basophil activation status was analyzed using activation markers CD203c and CD63. The results showed that there was no significant difference between EPT-positive and negative subjects for basophil activation status throughout EPT. Consequently, in vivo basophil activation after ingestion of the causative food may not be associated with EIARDs. New tests are desired for predicting EIARDs.",

keywords = "CD203c, CD63, basophil activation, exercise provocation test, exercise-induced allergic reactions on desensitization, oral immunotherapy",

author = "Jun Kunizaki and Shiro Sugiura and Akira Sakai and Miyuki Teshigawara and Atsushi Makino and Yoshihiro Takasato and Teruaki Matsui and Yasuto Kondo and Komei Ito",

note = "Publisher Copyright: 2023 Kunizaki, Sugiura, Sakai, Teshigawara, Makino, Takasato, Matsui, Kondo and Ito.",

year = "2023",

doi = "10.3389/falgy.2023.1298137",

language = "English",

volume = "4",

journal = "Frontiers in Allergy",

issn = "2673-6101",

publisher = "Frontiers Media SA",

}

TY - JOUR

T1 - Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients

AU - Kunizaki, Jun

AU - Sugiura, Shiro

AU - Sakai, Akira

AU - Teshigawara, Miyuki

AU - Makino, Atsushi

AU - Takasato, Yoshihiro

AU - Matsui, Teruaki

AU - Kondo, Yasuto

AU - Ito, Komei

N1 - Publisher Copyright: 2023 Kunizaki, Sugiura, Sakai, Teshigawara, Makino, Takasato, Matsui, Kondo and Ito.

PY - 2023

Y1 - 2023

N2 - Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose EIARD. EPT was performed on 20 participants, and in vivo basophil activation status was analyzed using activation markers CD203c and CD63. The results showed that there was no significant difference between EPT-positive and negative subjects for basophil activation status throughout EPT. Consequently, in vivo basophil activation after ingestion of the causative food may not be associated with EIARDs. New tests are desired for predicting EIARDs.

AB - Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose EIARD. EPT was performed on 20 participants, and in vivo basophil activation status was analyzed using activation markers CD203c and CD63. The results showed that there was no significant difference between EPT-positive and negative subjects for basophil activation status throughout EPT. Consequently, in vivo basophil activation after ingestion of the causative food may not be associated with EIARDs. New tests are desired for predicting EIARDs.

KW - CD203c

KW - CD63

KW - basophil activation

KW - exercise provocation test

KW - exercise-induced allergic reactions on desensitization

KW - oral immunotherapy

UR - https://www.scopus.com/pages/publications/85181737800

UR - https://www.scopus.com/pages/publications/85181737800#tab=citedBy

U2 - 10.3389/falgy.2023.1298137

DO - 10.3389/falgy.2023.1298137

M3 - Article

AN - SCOPUS:85181737800

SN - 2673-6101

VL - 4

JO - Frontiers in Allergy

JF - Frontiers in Allergy

M1 - 1298137

ER -

Evaluation of peripheral basophil activation during exercise provocation test for desensitized patients

抄録

UN SDG

All Science Journal Classification (ASJC) codes

文献へのアクセス

他のファイルとリンク

フィンガープリント

引用スタイル