Evaluation of systemic inflammatory responses in neonates with herpes simplex virus infection

Jun Ichi Kawada, Hiroshi Kimura, Yoshinori Ito, Yoshiniro Ando, Naoko Tanaka-Kitajima, Masahiro Hayakawa, Hiroyuki Nunoi, Fumio Endo, Tsuneo Morishima

研究成果: ジャーナルへの寄稿学術論文査読

37 被引用数 (Scopus)

抄録

Neonatal herpes simplex virus (HSV) infection is a severe disease with high mortality and morbidity. To investigate the pathogenesis of neonatal HSV infection, we examined inflammatory responses and markers of apoptosis in patients with neonatal HSV infection. Concentrations of inflammatory cytokines and markers of apoptosis were significantly higher in patients with disseminated HSV infection and were correlated with HSV load. It appears that the immunopathological damage that results from host responses to viral infection leads to organ dysfunction in patients with neonatal HSV infection.

本文言語英語
ページ(範囲)494-498
ページ数5
ジャーナルJournal of Infectious Diseases
190
3
DOI
出版ステータス出版済み - 01-08-2004
外部発表はい

All Science Journal Classification (ASJC) codes

  • 免疫アレルギー学
  • 感染症

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