Excretion of herpes simplex virus type 2 glycoprotein D into the culture medium

Takayuki Murata, Fumi Goshima, Hiroki Takakuwa, Yukihiro Nishiyama

研究成果: Article査読

4 被引用数 (Scopus)

抄録

Glycoprotein D (gD) of herpes simplex virus type 2 (HSV-2) was excreted from infected cells into the medium. Peptide mapping analysis and lectin binding assays suggested that the gD in the medium is secreted after full glycosylation and cleavage at its C terminus. Release of HSV-2 gD was inhibited by addition of either tunicamycin or brefeldin A, suggesting that the gD in the medium was secreted through the endoplasmic reticulum and Golgi apparatus.

本文言語English
ページ(範囲)2791-2795
ページ数5
ジャーナルJournal of General Virology
83
11
DOI
出版ステータスPublished - 01-11-2002
外部発表はい

All Science Journal Classification (ASJC) codes

  • ウイルス学

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