TY - JOUR
T1 - Fat embolism syndrome
T2 - An autopsy-proven case involving a patient on dialysis and systemic scleroderma
AU - Nishimura, Nahoko
AU - Banno, Shogo
AU - Kimura, Yukihiro
AU - Maeda, Sayaka
AU - Kobayashi, Mizuki
AU - Kawai, Kumi
AU - Suga, Norihiro
AU - Suzuki, Keisuke
AU - Miura, Naoto
AU - Yokoi, Toyoharu
AU - Imai, Hirokazu
PY - 2014/1/20
Y1 - 2014/1/20
N2 - A 66-year-old woman receiving continuous ambulatory peritoneal dialysis developed acute respiratory distress 12 hours after a fall. Blood gas analysis revealed hypoxia (PaO2 67.7 torr) and metabolic acidosis with an increased anion gap, consistent with lactic acidosis (lactate, 86.5 mg/dL; normal range, 4.0-16.0). Magnetic resonance imaging showed a lumbar vertebral body fracture. On the fourth hospital day, the patient died of multiorgan failure and disseminated intravascular coagulation. Postmortem studies revealed fat emboli in the systemic circulation, ie, fat embolism syndrome. Diagnosing fat embolism syndrome can be difficult in patients on dialysis or in those with collagen vascular or pulmonary diseases.
AB - A 66-year-old woman receiving continuous ambulatory peritoneal dialysis developed acute respiratory distress 12 hours after a fall. Blood gas analysis revealed hypoxia (PaO2 67.7 torr) and metabolic acidosis with an increased anion gap, consistent with lactic acidosis (lactate, 86.5 mg/dL; normal range, 4.0-16.0). Magnetic resonance imaging showed a lumbar vertebral body fracture. On the fourth hospital day, the patient died of multiorgan failure and disseminated intravascular coagulation. Postmortem studies revealed fat emboli in the systemic circulation, ie, fat embolism syndrome. Diagnosing fat embolism syndrome can be difficult in patients on dialysis or in those with collagen vascular or pulmonary diseases.
KW - Acute respiratory distress
KW - Diagnostic criteria
KW - Fat embolism syndrome
KW - Hypoxia
KW - Lactic acidosis
UR - https://www.scopus.com/pages/publications/84892711994
UR - https://www.scopus.com/pages/publications/84892711994#tab=citedBy
U2 - 10.4137/CCRep.S12636
DO - 10.4137/CCRep.S12636
M3 - Article
AN - SCOPUS:84892711994
SN - 1179-5476
VL - 7
SP - 7
EP - 12
JO - Clinical Medicine Insights: Case Reports
JF - Clinical Medicine Insights: Case Reports
ER -