Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome

Itaru Yanagihara, Koji Inui, Keiko Yanagihara, Yong Dong Park, Junko Tanaka, Keiichi Ozono, Shintaro Okada, Hiroki Kurahashi

研究成果: Article

6 引用 (Scopus)

抜粋

We used a dual-color fluorescence in situ hybridization technique to estimate deleted mitochondrial DNA at a single-cell level and determine any correlation with the disease progression in lymphocytes from patients with Pearson marrow-pancreas syndrome. The method demonstrated a shift in heteroplasmy, paralleling the hematologic improvement.

元の言語English
ページ(範囲)452-455
ページ数4
ジャーナルJournal of Pediatrics
139
発行部数3
DOI
出版物ステータスPublished - 01-01-2001
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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