Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome

Itaru Yanagihara; Koji Inui; Keiko Yanagihara; Yong Dong Park; Junko Tanaka; Keiichi Ozono; Shintaro Okada; Hiroki Kurahashi

doi:10.1067/mpd.2001.116296

Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome

Itaru Yanagihara
, Koji Inui
, Keiko Yanagihara
, Yong Dong Park
, Junko Tanaka
, Keiichi Ozono
, Shintaro Okada
, Hiroki Kurahashi

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

13 被引用数 (Scopus)

抄録

We used a dual-color fluorescence in situ hybridization technique to estimate deleted mitochondrial DNA at a single-cell level and determine any correlation with the disease progression in lymphocytes from patients with Pearson marrow-pancreas syndrome. The method demonstrated a shift in heteroplasmy, paralleling the hematologic improvement.

本文言語	英語
ページ（範囲）	452-455
ページ数	4
ジャーナル	Journal of Pediatrics
巻	139
号	3
DOI	https://doi.org/10.1067/mpd.2001.116296
出版ステータス	出版済み - 2001
外部発表	はい

All Science Journal Classification (ASJC) codes

小児科学、周産期医学および子どもの健康

文献へのアクセス

10.1067/mpd.2001.116296

他のファイルとリンク

引用スタイル

@article{ca1afa7df03044d0b2ff244ddc4f1e9e,

title = "Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome",

abstract = "We used a dual-color fluorescence in situ hybridization technique to estimate deleted mitochondrial DNA at a single-cell level and determine any correlation with the disease progression in lymphocytes from patients with Pearson marrow-pancreas syndrome. The method demonstrated a shift in heteroplasmy, paralleling the hematologic improvement.",

author = "Itaru Yanagihara and Koji Inui and Keiko Yanagihara and Park, \{Yong Dong\} and Junko Tanaka and Keiichi Ozono and Shintaro Okada and Hiroki Kurahashi",

note = "Funding Information: Supported in part by grants from the Ministry of Education of Japan. ",

year = "2001",

doi = "10.1067/mpd.2001.116296",

language = "English",

volume = "139",

pages = "452--455",

journal = "Journal of Pediatrics",

issn = "0022-3476",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome

AU - Yanagihara, Itaru

AU - Inui, Koji

AU - Yanagihara, Keiko

AU - Park, Yong Dong

AU - Tanaka, Junko

AU - Ozono, Keiichi

AU - Okada, Shintaro

AU - Kurahashi, Hiroki

N1 - Funding Information: Supported in part by grants from the Ministry of Education of Japan.

PY - 2001

Y1 - 2001

N2 - We used a dual-color fluorescence in situ hybridization technique to estimate deleted mitochondrial DNA at a single-cell level and determine any correlation with the disease progression in lymphocytes from patients with Pearson marrow-pancreas syndrome. The method demonstrated a shift in heteroplasmy, paralleling the hematologic improvement.

AB - We used a dual-color fluorescence in situ hybridization technique to estimate deleted mitochondrial DNA at a single-cell level and determine any correlation with the disease progression in lymphocytes from patients with Pearson marrow-pancreas syndrome. The method demonstrated a shift in heteroplasmy, paralleling the hematologic improvement.

UR - https://www.scopus.com/pages/publications/0034835014

UR - https://www.scopus.com/pages/publications/0034835014#tab=citedBy

U2 - 10.1067/mpd.2001.116296

DO - 10.1067/mpd.2001.116296

M3 - Article

C2 - 11562629

AN - SCOPUS:0034835014

SN - 0022-3476

VL - 139

SP - 452

EP - 455

JO - Journal of Pediatrics

JF - Journal of Pediatrics

IS - 3

ER -

Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome

抄録

All Science Journal Classification (ASJC) codes

文献へのアクセス

他のファイルとリンク

フィンガープリント

引用スタイル