Follicular variant of peripheral T-cell lymphoma mimicking follicular lymphoma: A case report with a review of the Literature

Naoe Goto, Hisashi Tsurumi, Michio Sawada, Nobuhiro Kanemura, Takeshi Hara, Senji Kasahara, Yusuke Kito, Katsuyoshi Takada, Yasuharu Sato, Tadashi Yoshino, Hisataka Moriwaki, Tsuyoshi Takami

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Peripheral T-cell lymphoma (PTCL) with a follicular growth pattern is very rare. Herein, a case of follicular variant of PTCL in a 50-year-old man who complained of tonsillar and generalized lymph node swelling is reported. The resected tonsil revealed a vague nodular growth pattern of atypical cells, medium to large in size, with abundant pale cytoplasm. The lymphoma cells were CD3 + CD4 + CD5 + CD8 - CD10 + CD56 - CD57 - BCL6 + PD-1 + CXCL13 + and were associated with a meshwork of CD21 + follicular dendritic cells. Molecular studies revealed clonal rearrangement of the T-cell receptor gamma chain gene but not of the immunoglobulin gene. Cytogenetic analysis disclosed a complex abnormality in 18 of 20 cells with the exclusion of t(5; 9). These findings suggest that the present case is a follicular variant of PTCL derived from follicular T-helper cells.

本文言語English
ページ(範囲)326-330
ページ数5
ジャーナルPathology International
61
5
DOI
出版ステータスPublished - 05-2011
外部発表はい

All Science Journal Classification (ASJC) codes

  • 病理学および法医学

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