Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis

Tomomitsu Tahara, Tomoyuki Shibata, Masakatsu Nakamura, Daisuke Yoshioka, Masaaki Okubo, Tomiyasu Arisawa, Ichiro Hirata

研究成果: Article

99 引用 (Scopus)

抄録

Background: Magnifying narrow-band imaging (NBI) endoscopy clearly visualizes superficial gastric mucosal patterns and capillary patterns. Objective: To investigate gastric mucosal patterns by using magnifying NBI endoscopy and identify any relationship between those patterns and Helicobacter pylori-induced gastritis. Design: Gastric mucosal patterns seen with magnifying NBI in uninvolved gastric corpus were divided into the following categories: normal-small, round pits with regular subepithelial capillary networks; type 1-slightly enlarged, round pits with unclear or irregular subepithelial capillary networks; type 2-obviously enlarged, oval or prolonged pits with increased density of irregular vessels; and type 3-well-demarcated oval or tubulovillous pits with clearly visible coiled or wavy vessels. Setting: Department of Gastroenterology, Fujita Health University. Patients: This study involved 106 participants undergoing upper endoscopy. Results: H pylori infection-positive ratios of normal and types 1, 2, and 3 patterns were 7.5%, 92.9%, 94.5%, and 66.7%, respectively. Sensitivity and specificity for types 1 + 2 + 3 for detection of H pylori positivity and type 3 for detection of intestinal metaplasia were 95.2%, 82.2%, 73.3%, and 95.6%, respectively. Development of mucosal patterns from normal to types 1, 2, and 3 was correlated with all histological parameters (P < .0001), lower pepsinogen I/II ratios (P < .0001), and degree of endoscopic atrophy (P < .0001). Sensitivity and specificity of type 3 for the prediction of severe histological atrophy was also better than those of serum pepsinogen level and standard endoscopy. Limitations: Only 1 endoscopist performed endoscopic procedures, and interobserver agreement could not be assessed. Conclusions: Magnifying NBI endoscopy is useful for predicting H pylori infection and the histological severity of gastritis and is valuable for predicting gastric atrophy in the entire stomach.

元の言語English
ページ(範囲)246-253
ページ数8
ジャーナルGastrointestinal Endoscopy
70
発行部数2
DOI
出版物ステータスPublished - 01-08-2009

Fingerprint

Narrow Band Imaging
Gastritis
Endoscopy
Stomach
Pylorus
Atrophy
Pepsinogen A
Pepsinogen C
Sensitivity and Specificity
Metaplasia
Gastroenterology
Infection
Helicobacter pylori
Health
Serum

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

これを引用

Tahara, Tomomitsu ; Shibata, Tomoyuki ; Nakamura, Masakatsu ; Yoshioka, Daisuke ; Okubo, Masaaki ; Arisawa, Tomiyasu ; Hirata, Ichiro. / Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis. :: Gastrointestinal Endoscopy. 2009 ; 巻 70, 番号 2. pp. 246-253.
@article{89e3ce3f7c734ead97f64bbb15011d29,
title = "Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis",
abstract = "Background: Magnifying narrow-band imaging (NBI) endoscopy clearly visualizes superficial gastric mucosal patterns and capillary patterns. Objective: To investigate gastric mucosal patterns by using magnifying NBI endoscopy and identify any relationship between those patterns and Helicobacter pylori-induced gastritis. Design: Gastric mucosal patterns seen with magnifying NBI in uninvolved gastric corpus were divided into the following categories: normal-small, round pits with regular subepithelial capillary networks; type 1-slightly enlarged, round pits with unclear or irregular subepithelial capillary networks; type 2-obviously enlarged, oval or prolonged pits with increased density of irregular vessels; and type 3-well-demarcated oval or tubulovillous pits with clearly visible coiled or wavy vessels. Setting: Department of Gastroenterology, Fujita Health University. Patients: This study involved 106 participants undergoing upper endoscopy. Results: H pylori infection-positive ratios of normal and types 1, 2, and 3 patterns were 7.5{\%}, 92.9{\%}, 94.5{\%}, and 66.7{\%}, respectively. Sensitivity and specificity for types 1 + 2 + 3 for detection of H pylori positivity and type 3 for detection of intestinal metaplasia were 95.2{\%}, 82.2{\%}, 73.3{\%}, and 95.6{\%}, respectively. Development of mucosal patterns from normal to types 1, 2, and 3 was correlated with all histological parameters (P < .0001), lower pepsinogen I/II ratios (P < .0001), and degree of endoscopic atrophy (P < .0001). Sensitivity and specificity of type 3 for the prediction of severe histological atrophy was also better than those of serum pepsinogen level and standard endoscopy. Limitations: Only 1 endoscopist performed endoscopic procedures, and interobserver agreement could not be assessed. Conclusions: Magnifying NBI endoscopy is useful for predicting H pylori infection and the histological severity of gastritis and is valuable for predicting gastric atrophy in the entire stomach.",
author = "Tomomitsu Tahara and Tomoyuki Shibata and Masakatsu Nakamura and Daisuke Yoshioka and Masaaki Okubo and Tomiyasu Arisawa and Ichiro Hirata",
year = "2009",
month = "8",
day = "1",
doi = "10.1016/j.gie.2008.11.046",
language = "English",
volume = "70",
pages = "246--253",
journal = "Gastrointestinal Endoscopy",
issn = "0016-5107",
publisher = "Mosby Inc.",
number = "2",

}

Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis. / Tahara, Tomomitsu; Shibata, Tomoyuki; Nakamura, Masakatsu; Yoshioka, Daisuke; Okubo, Masaaki; Arisawa, Tomiyasu; Hirata, Ichiro.

:: Gastrointestinal Endoscopy, 巻 70, 番号 2, 01.08.2009, p. 246-253.

研究成果: Article

TY - JOUR

T1 - Gastric mucosal pattern by using magnifying narrow-band imaging endoscopy clearly distinguishes histological and serological severity of chronic gastritis

AU - Tahara, Tomomitsu

AU - Shibata, Tomoyuki

AU - Nakamura, Masakatsu

AU - Yoshioka, Daisuke

AU - Okubo, Masaaki

AU - Arisawa, Tomiyasu

AU - Hirata, Ichiro

PY - 2009/8/1

Y1 - 2009/8/1

N2 - Background: Magnifying narrow-band imaging (NBI) endoscopy clearly visualizes superficial gastric mucosal patterns and capillary patterns. Objective: To investigate gastric mucosal patterns by using magnifying NBI endoscopy and identify any relationship between those patterns and Helicobacter pylori-induced gastritis. Design: Gastric mucosal patterns seen with magnifying NBI in uninvolved gastric corpus were divided into the following categories: normal-small, round pits with regular subepithelial capillary networks; type 1-slightly enlarged, round pits with unclear or irregular subepithelial capillary networks; type 2-obviously enlarged, oval or prolonged pits with increased density of irregular vessels; and type 3-well-demarcated oval or tubulovillous pits with clearly visible coiled or wavy vessels. Setting: Department of Gastroenterology, Fujita Health University. Patients: This study involved 106 participants undergoing upper endoscopy. Results: H pylori infection-positive ratios of normal and types 1, 2, and 3 patterns were 7.5%, 92.9%, 94.5%, and 66.7%, respectively. Sensitivity and specificity for types 1 + 2 + 3 for detection of H pylori positivity and type 3 for detection of intestinal metaplasia were 95.2%, 82.2%, 73.3%, and 95.6%, respectively. Development of mucosal patterns from normal to types 1, 2, and 3 was correlated with all histological parameters (P < .0001), lower pepsinogen I/II ratios (P < .0001), and degree of endoscopic atrophy (P < .0001). Sensitivity and specificity of type 3 for the prediction of severe histological atrophy was also better than those of serum pepsinogen level and standard endoscopy. Limitations: Only 1 endoscopist performed endoscopic procedures, and interobserver agreement could not be assessed. Conclusions: Magnifying NBI endoscopy is useful for predicting H pylori infection and the histological severity of gastritis and is valuable for predicting gastric atrophy in the entire stomach.

AB - Background: Magnifying narrow-band imaging (NBI) endoscopy clearly visualizes superficial gastric mucosal patterns and capillary patterns. Objective: To investigate gastric mucosal patterns by using magnifying NBI endoscopy and identify any relationship between those patterns and Helicobacter pylori-induced gastritis. Design: Gastric mucosal patterns seen with magnifying NBI in uninvolved gastric corpus were divided into the following categories: normal-small, round pits with regular subepithelial capillary networks; type 1-slightly enlarged, round pits with unclear or irregular subepithelial capillary networks; type 2-obviously enlarged, oval or prolonged pits with increased density of irregular vessels; and type 3-well-demarcated oval or tubulovillous pits with clearly visible coiled or wavy vessels. Setting: Department of Gastroenterology, Fujita Health University. Patients: This study involved 106 participants undergoing upper endoscopy. Results: H pylori infection-positive ratios of normal and types 1, 2, and 3 patterns were 7.5%, 92.9%, 94.5%, and 66.7%, respectively. Sensitivity and specificity for types 1 + 2 + 3 for detection of H pylori positivity and type 3 for detection of intestinal metaplasia were 95.2%, 82.2%, 73.3%, and 95.6%, respectively. Development of mucosal patterns from normal to types 1, 2, and 3 was correlated with all histological parameters (P < .0001), lower pepsinogen I/II ratios (P < .0001), and degree of endoscopic atrophy (P < .0001). Sensitivity and specificity of type 3 for the prediction of severe histological atrophy was also better than those of serum pepsinogen level and standard endoscopy. Limitations: Only 1 endoscopist performed endoscopic procedures, and interobserver agreement could not be assessed. Conclusions: Magnifying NBI endoscopy is useful for predicting H pylori infection and the histological severity of gastritis and is valuable for predicting gastric atrophy in the entire stomach.

UR - http://www.scopus.com/inward/record.url?scp=67651121768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67651121768&partnerID=8YFLogxK

U2 - 10.1016/j.gie.2008.11.046

DO - 10.1016/j.gie.2008.11.046

M3 - Article

C2 - 19386303

AN - SCOPUS:67651121768

VL - 70

SP - 246

EP - 253

JO - Gastrointestinal Endoscopy

JF - Gastrointestinal Endoscopy

SN - 0016-5107

IS - 2

ER -