Genetic association study of KREMEN1 and DKK1 and schizophrenia in a Japanese population

Branko Aleksic, Itaru Kushima, Yoshihito Ito, Yukako Nakamura, Hiroshi Ujike, Michio Suzuki, Toshiya Inada, Ryota Hashimoto, Masatoshi Takeda, Nakao Iwata, Norio Ozaki

研究成果: Article査読

11 被引用数 (Scopus)

抄録

The aim of the current study was to examine the association of KREMEN1 and DKK1, two wnt pathway-related genes with schizophrenia in Japanese subjects. We genotyped 16 common genetic variants within the aforementioned genes and examined their associations with schizophrenia. Results demonstrated that a common variant in the promoter region of KREMEN1 might modulate the risk of schizophrenia in the Japanese. However, further replication will be needed for conclusive interpretation of the effect of this locus on the pathogenesis of schizophrenia.

本文言語English
ページ(範囲)113-117
ページ数5
ジャーナルSchizophrenia Research
118
1-3
DOI
出版ステータスPublished - 05-2010

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Biological Psychiatry

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